caa a22 4500 606216677 CHVBK 20210128101104.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00701-014-2316-1 doi (NATIONALLICENCE)springer-10.1007/s00701-014-2316-1 Brain surface reformatted imaging (BSRI) for intraoperative neuronavigation in brain tumor surgery [Elektronische Daten] [Marie-Therese Forster, Nadja Heindl, Elke Hattingen, Florian Gessler, Johanna Quick, Volker Seifert, Christian Senft] Background: For safe resection of lesions situated in or near eloquent brain regions, determination of their spatial and functional relationship is crucial. Since functional magnetic resonance imaging and intraoperative neurophysiological mapping are not available in all neurosurgical departments, we aimed to evaluate brain surface reformatted imaging (BSRI) as an additional display mode for neuronavigation. Methods: Eight patients suffering from perirolandic tumors were preoperatively studied with MRI and navigated transcranial magnetic stimulation (nTMS). Afterwards, the MRI was automatically transformed into BSR images in neuronavigation software (Brainlab, Brainlab AG, Feldkirchen, Germany). One experienced neuroradiologist, one experienced neurosurgeon, and two residents determined hand representation areas ipsilateral to each tumor on two-dimensional (2D) MR images and on BSR images. All results were compared to results from intraoperative direct cortical mapping of the hand motor cortex and to preoperative nTMS results. Results: Findings from nTMS and intraoperative direct cortical mapping of the hand motor cortex were congruent in all cases. Hand representation areas were correctly determined on BSR images in 81.3% and on 2D-MR images in 93.75% (p = 0.26). In a subgroup analysis, experienced observers showed more familiarity with BSRI than residents (96.9 vs. 84.4% correct results, p = 0.19), with an equal error rate for 2D-MRI. The time required to define hand representation areas was significantly shorter using BSRI than using standard MRI (mean 27.4 vs. 40.4s, p = 0.04). Conclusions: With BSRI, a new method for neuronavigation is now available, allowing fast and easy intraoperative localization of distinct brain regions. Springer-Verlag Wien, 2015 Brain surface reformatted imaging nationallicence Neuronavigation nationallicence Direct cortical stimulation nationallicence Transcranial magnetic stimulation nationallicence Forster Marie-Therese Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut Heindl Nadja Brainlab AG, Kapellenstrasse 12, 85622, Feldkirchen, Germany aut Hattingen Elke Department of Neuroradiology, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut Gessler Florian Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut Quick Johanna Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut Seifert Volker Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut Senft Christian Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 265-274 0001-6268 157:2<265 2015 157 701 https://doi.org/10.1007/s00701-014-2316-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-014-2316-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Forster Marie-Therese Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Heindl Nadja Brainlab AG, Kapellenstrasse 12, 85622, Feldkirchen, Germany aut NATIONALLICENCE 700 1- Hattingen Elke Department of Neuroradiology, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Gessler Florian Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Quick Johanna Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Seifert Volker Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Senft Christian Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/2(2015-02-01), 265-274 0001-6268 157:2<265 2015 157 701