caa a22 4500 606216790 CHVBK 20210128101105.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00701-015-2590-6 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2590-6 Training for brain tumour resection: a realistic model with easy accessibility [Elektronische Daten] [Marcel Kamp, Johannes Knipps, Hans-Jakob Steiger, Marion Rapp, Jan Cornelius, Stefanie Folke-Sabel, Michael Sabel] Background: Resection of intrinsic and extrinsic brain tumours requires an understanding of sulcal and gyral anatomy, familiarity with tissue consistency and tissue manipulation. As yet, these skills are acquired by observation and supervised manipulation during surgery, thus accepting a potential learning curve at the expense of the patient in a live surgical situation. A brain tumour model could ensure optimised manual skills and understanding of surgical anatomy acquired in an elective and relaxed teaching situation. We report and evaluate a brain tumour model, regarding availability, realistic representation of sulcal and gyral anatomy and tissue consistency. Method: Freshly prepared agar-agar solution with different concentrations was added with highlighter ink and injected into fresh sheep brains. Results: Hardened agar-agar solution formed masses comparable to malignant brain tumours. Variation of the agar-agar concentration influenced diffusion of agar-agar solution in the adjacent brain tissue. Higher concentrated agar-agar solutions formed sharply delimitated masses mimicking cerebral metastases and lower concentrated agar-agar solutions tended to diffuse into the adjacent cerebral tissue. Adding highlighter ink to the agar-agar solution produced fluorescence after blue light excitation comparable to the 5-ALA induced fluorescence of malignant glioma. Conclusions: The described in vitro sheep brain tumour model is simple and realistic, available practically everywhere and cheap. Therefore, it could be useful for young neurosurgical residents to acquire basic neuro-oncological skills, experiencing properties of the cerebral brain texture and its haptic perception and to learn handling of neurosurgical equipment. Springer-Verlag Wien, 2015 Metastases nationallicence Glioma nationallicence Brain tumour nationallicence Resident training nationallicence Skill nationallicence Kamp Marcel Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Knipps Johannes Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Steiger Hans-Jakob Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Rapp Marion Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Cornelius Jan Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Folke-Sabel Stefanie Stem Cell Network North Rhine-Westphalia, Voelklinger Strasse 49, 40221, Duesseldorf, Germany aut Sabel Michael Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut Acta Neurochirurgica Springer Vienna 157/11(2015-11-01), 1975-1981 0001-6268 157:11<1975 2015 157 701 https://doi.org/10.1007/s00701-015-2590-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 brief-communication jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2590-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kamp Marcel Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Knipps Johannes Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Steiger Hans-Jakob Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Rapp Marion Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Cornelius Jan Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Folke-Sabel Stefanie Stem Cell Network North Rhine-Westphalia, Voelklinger Strasse 49, 40221, Duesseldorf, Germany aut NATIONALLICENCE 700 1- Sabel Michael Department of Neurosurgery, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/11(2015-11-01), 1975-1981 0001-6268 157:11<1975 2015 157 701