caa a22 4500 606216898 CHVBK 20210128101105.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00701-015-2582-6 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2582-6 A review of spontaneous intracranial extradural hematoma in sickle-cell disease [Elektronische Daten] [Samantha Hettige, Agbolahan Sofela, Sanj Bassi, Chris Chandler] Sickle-cell disease is common among patients of Afro-Caribbean origin. Though it can precipitate neurological conditions, it only rarely causes neurosurgical problems, with very few reported cases. We describe the case of a 7-year-old girl with a background of sickle-cell disease (SCD) brought into an acute neurosurgical unit in extremis, signs of a raised ICP, and with no history of recent trauma. Following further investigations, an acute drop in the hemoglobin and hematocrit levels were noted, with the cause of her presentation being attributed to a sickling crisis causing skull convexity infarction and resulting in spontaneous bilateral extradural hematomas requiring emergency evacuation. We review the current literature and propose the pathophysiological mechanism behind this phenomenon. Springer-Verlag Wien, 2015 Sickle-cell disease nationallicence Extradural hematoma nationallicence Skull convexity infarct nationallicence Spontaneous nationallicence Non-traumatic nationallicence Hettige Samantha Department of Neurosurgery, King's College Hospital, London, UK aut Sofela Agbolahan Department of Neurosurgery, King's College Hospital, London, UK aut Bassi Sanj Department of Neurosurgery, King's College Hospital, London, UK aut Chandler Chris Department of Neurosurgery, King's College Hospital, London, UK aut Acta Neurochirurgica Springer Vienna 157/11(2015-11-01), 2025-2029 0001-6268 157:11<2025 2015 157 701 https://doi.org/10.1007/s00701-015-2582-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2582-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hettige Samantha Department of Neurosurgery, King's College Hospital, London, UK aut NATIONALLICENCE 700 1- Sofela Agbolahan Department of Neurosurgery, King's College Hospital, London, UK aut NATIONALLICENCE 700 1- Bassi Sanj Department of Neurosurgery, King's College Hospital, London, UK aut NATIONALLICENCE 700 1- Chandler Chris Department of Neurosurgery, King's College Hospital, London, UK aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/11(2015-11-01), 2025-2029 0001-6268 157:11<2025 2015 157 701