caa a22 4500 606216901 CHVBK 20210128101105.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00701-015-2548-8 doi (NATIONALLICENCE)springer-10.1007/s00701-015-2548-8 Early carotid artery stenting for symptomatic carotid artery stenosis [Elektronische Daten] [Kyung Song, O-Ki Kwon, Gyojun Hwang, Hee-Joon Bae, Moon-Ku Han, Beom Kim, Jae Bang, Chang Oh] Background: The aim of present study was to assess safety and efficacy of early carotid artery stent (CAS) in patients with symptomatic carotid artery stenosis compared with delayed CAS. Methods: This retrospective study was approved by the institutional review board, and the requirement to obtain written informed consent was waived. Outcomes of 206 patients with symptomatic carotid stenosis who were treated by CAS were analyzed. According to CAS timing from last symptom, patients were divided into early (within 2weeks, 74 [35.0%]) and delayed (after 2weeks, 112 [64.1%]) group by CAS timing from the last symptom. Procedural complication and early (≤30days of CAS) event (ipsilateral stroke or any death) for safety, and late (31days to 1year of CAS) event for efficacy of CAS preventing further stroke were evaluated. The two groups were compared using Cox proportional hazard analysis. Results: No difference was found in procedural complication between the groups (early 2 [2.7%] vs. delayed group 7 [5.3%], hazard ratio [HR] 0.61, 95% confidence interval [CI] 0.123-2.979, p = 0.537). In the early group, however, early event developed more frequently than in the late group (9 [12.2%] vs. 1 [0.8%], HR 16.05, 95% CI 1.991-129.438, p = 0.009). The late event rate showed no difference between the two groups (4 [5.4%] vs. 4 [3.0%], HR 2.09, 95% CI 0.484-8.989, p = 0.324). Conclusions: Early CAS is not safe during periprocedural period, compared with late CAS. In CAS for symptomatic carotid stenosis, delayed CAS should be considered. Springer-Verlag Wien, 2015 Carotid artery stenosis nationallicence Early carotid artery stenting nationallicence Delayed carotid stenting nationallicence Complications nationallicence Song Kyung Department of Neurosurgery, Neurovascular Center of New Korea Hospital, Gimpo, Gyeonggi Province, South Korea aut Kwon O-Ki Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut Hwang Gyojun Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut Bae Hee-Joon Department of Neurology, Seoul National University College of Medicine, Bundang Hospital, Seongnam, South Korea aut Han Moon-Ku Department of Neurology, Seoul National University College of Medicine, Bundang Hospital, Seongnam, South Korea aut Kim Beom Department of Neurology, Seoul National University College of Medicine, Bundang Hospital, Seongnam, South Korea aut Bang Jae Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut Oh Chang Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut Acta Neurochirurgica Springer Vienna 157/11(2015-11-01), 1873-1878 0001-6268 157:11<1873 2015 157 701 https://doi.org/10.1007/s00701-015-2548-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00701-015-2548-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Song Kyung Department of Neurosurgery, Neurovascular Center of New Korea Hospital, Gimpo, Gyeonggi Province, South Korea aut NATIONALLICENCE 700 1- Kwon O-Ki Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut NATIONALLICENCE 700 1- Hwang Gyojun Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut NATIONALLICENCE 700 1- Bae Hee-Joon Department of Neurology, Seoul National University College of Medicine, Bundang Hospital, Seongnam, South Korea aut NATIONALLICENCE 700 1- Han Moon-Ku Department of Neurology, Seoul National University College of Medicine, Bundang Hospital, Seongnam, South Korea aut NATIONALLICENCE 700 1- Kim Beom Department of Neurology, Seoul National University College of Medicine, Bundang Hospital, Seongnam, South Korea aut NATIONALLICENCE 700 1- Bang Jae Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut NATIONALLICENCE 700 1- Oh Chang Department of Neurosurgery, Seoul National University College of Medicine, Bundang Hospital, 300 Gumi-dong, Bungdang-gu, 463-707, Seongnam, Gyeonggi, South Korea aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer Vienna 157/11(2015-11-01), 1873-1878 0001-6268 157:11<1873 2015 157 701