caa a22 4500 60622050X CHVBK 20210128101124.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00380-013-0452-9 doi (NATIONALLICENCE)springer-10.1007/s00380-013-0452-9 Evaluation of coronary artery disease and cardiac morphology and function in patients with hypertrophic cardiomyopathy, using cardiac computed tomography [Elektronische Daten] [Satoshi Okayama, Tsunenari Soeda, Rika Kawakami, Yasuhiro Takami, Satoshi Somekawa, Tomoya Ueda, Yu Sugawara, Takaki Matsumoto, Ji Sung, Taku Nishida, Shiro Uemura, Yoshihiko Saito] Coronary artery disease and cardiac morphology and function were evaluated in 51 patients with hypertrophic cardiomyopathy (HCM), without typical chest pain, using cardiac computed tomography (CT). This study investigated the prevalence of coronary artery disease, the indicators of obstructive coronary stenosis, and the magnitude of left ventricular (LV) hypertrophy. The patients' mean coronary artery calcium score was 198.8 ± 312.0 and was positively correlated with the number of coronary risk factors (r = 0.32; P < 0.05). Of the 51 patients with HCM, 42 (82.4 %) had some degree of stenosis and 8 (15.7 %) had obstructive stenosis. Noncalcified and mixed plaques were detected in 14 (27.5 %) and 11 (21.6 %) patients, respectively. Multivariate logistic regression revealed that diabetes was an independent indicator of the presence of obstructive stenosis in HCM patients. Multivariate linear regression revealed that low estimated glomerular filtration rates and high triglyceride concentrations were independent indicators of higher LV mass indexes. In conclusion, cardiac CT revealed that coronary artery disease was common among patients with HCM. The presence of obstructive coronary stenosis and the magnitude of LV hypertrophy were related to the presence of diabetes, triglyceride levels, and estimated glomerular filtration rate. Springer Japan, 2013 Hypertrophic cardiomyopathy nationallicence Coronary artery disease nationallicence Computed tomography nationallicence Diabetes nationallicence Okayama Satoshi First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Soeda Tsunenari First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Kawakami Rika First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Takami Yasuhiro First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Somekawa Satoshi First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Ueda Tomoya First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Sugawara Yu First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Matsumoto Takaki First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Sung Ji Department of Cardiology, Yamato-Kashihara Hospital, Nara, Japan aut Nishida Taku First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Uemura Shiro First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Saito Yoshihiko First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut Heart and Vessels Springer Japan 30/1(2015-01-01), 28-35 0910-8327 30:1<28 2015 30 380 https://doi.org/10.1007/s00380-013-0452-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-013-0452-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Okayama Satoshi First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Soeda Tsunenari First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Kawakami Rika First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Takami Yasuhiro First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Somekawa Satoshi First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Ueda Tomoya First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Sugawara Yu First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Matsumoto Takaki First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Sung Ji Department of Cardiology, Yamato-Kashihara Hospital, Nara, Japan aut NATIONALLICENCE 700 1- Nishida Taku First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Uemura Shiro First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 700 1- Saito Yoshihiko First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Nara, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/1(2015-01-01), 28-35 0910-8327 30:1<28 2015 30 380