caa a22 4500 606220585 CHVBK 20210128101124.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00380-013-0450-y doi (NATIONALLICENCE)springer-10.1007/s00380-013-0450-y Natural history of low-intensity neointimal tissue after an everolimus-eluting stent implantation: a serial observation with optical coherence tomography [Elektronische Daten] [Masahiko Shibuya, Kenichi Fujii, Masashi Fukunaga, Takahiro Imanaka, Kojiro Miki, Hiroto Tamaru, Mitsumasa Ohyanagi, Tohru Masuyama] Although previous optical coherence tomography (OCT) studies reported that restenosis tissue after implantation of a drug-eluting stent (DES) was composed of a variety of cells, the clinical significance of morphologic characteristics for in-stent neointimal tissue as assessed by OCT has not been clarified. We experienced a patient with stable angina who underwent percutaneous coronary intervention with a 2.5 × 18-mm DES implantation 6 months before the OCT examination. OCT imaging showed a mild intimal hyperplasia (39 % neointimal hyperplasia) with eccentric, heterogeneous tissue, predominantly of low signal intensity. Seventeen months after the initial procedure, OCT revealed a significant increase in percent neointimal hyperplasia of 58 %, with morphologically different intimal tissue of concentric homogeneous high intensity in the stented segments. This finding suggests that low-intensity intimal tissue morphology detected by OCT could be a morphometric predictor of late neointimal tissue growth after DES implantation. Springer Japan, 2013 Optical coherence tomography nationallicence Drug-eluting stent nationallicence Intimal hyperplasia nationallicence Coronary artery disease nationallicence Shibuya Masahiko Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Fujii Kenichi Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Fukunaga Masashi Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Imanaka Takahiro Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Miki Kojiro Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Tamaru Hiroto Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Ohyanagi Mitsumasa Division of Coronary Heart Disease, Hyogo College of Medicine, Nishinomiya, Japan aut Masuyama Tohru Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut Heart and Vessels Springer Japan 30/1(2015-01-01), 136-139 0910-8327 30:1<136 2015 30 380 https://doi.org/10.1007/s00380-013-0450-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-013-0450-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shibuya Masahiko Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Fujii Kenichi Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Fukunaga Masashi Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Imanaka Takahiro Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Miki Kojiro Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Tamaru Hiroto Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Ohyanagi Mitsumasa Division of Coronary Heart Disease, Hyogo College of Medicine, Nishinomiya, Japan aut NATIONALLICENCE 700 1- Masuyama Tohru Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, 6638501, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/1(2015-01-01), 136-139 0910-8327 30:1<136 2015 30 380