caa a22 4500 606220747 CHVBK 20210128101125.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00380-014-0546-z doi (NATIONALLICENCE)springer-10.1007/s00380-014-0546-z Usefulness of serum bilirubin levels as a biomarker for long-term clinical outcomes after percutaneous coronary intervention [Elektronische Daten] [Hyun-Wook Kim, Dong-Hyun Choi, Leejin Lim, Young-Min Lee, Joon Kang, Seung Chae, Young-Jae Ki, Heesang Song, Young-Youp Koh] The aim of this study was to evaluate the prognostic value of serum total bilirubin on the development of adverse outcomes after percutaneous coronary intervention (PCI) besides high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B type natriuretic peptide (NT-proBNP). Serum total bilirubin, hs-cTnT, and NT-proBNP were analyzed in 372 patients who underwent PCI. The primary endpoint was cardiac death. There were 21 events of cardiac death during a mean of 25.8months of follow-up. When the serum total bilirubin cut-off level (median value) was set to 0.58mg/dL using the receiver operating characteristic curve, the sensitivity was 95.2% and the specificity was 51.0% for differentiating between the group with cardiac death and the group without cardiac death. Kaplan-Meier analysis revealed that the lower serum total bilirubin group (<0.58mg/dL) had a significantly higher cardiac death rate than the higher serum total bilirubin group (≥0.58mg/dL) (10.4 vs. 0.6%, log-rank: P=0.0001). In conclusion, low serum total bilirubin is a predictive marker for cardiac death after PCI. Springer Japan, 2014 Bilirubin nationallicence Troponin T nationallicence N-terminal pro-BNP nationallicence Percutaneous coronary intervention nationallicence Cardiac death nationallicence Kim Hyun-Wook Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut Choi Dong-Hyun Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut Lim Leejin Department of Biomaterials, Chosun University Graduate School, 501-759, Gwangju, Republic of Korea aut Lee Young-Min Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut Kang Joon Department of Internal Medicine, Mokpo Jung-ang General Hospital, Mokpo, Republic of Korea aut Chae Seung Department of Internal Medicine, Mokpo Jung-ang General Hospital, Mokpo, Republic of Korea aut Ki Young-Jae Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut Song Heesang Department of Biochemistry and Molecular Biology, Chosun University School of Medicine, 501-759, Gwangju, Republic of Korea aut Koh Young-Youp Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut Heart and Vessels Springer Japan 30/6(2015-11-01), 728-733 0910-8327 30:6<728 2015 30 380 https://doi.org/10.1007/s00380-014-0546-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0546-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Hyun-Wook Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 700 1- Choi Dong-Hyun Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 700 1- Lim Leejin Department of Biomaterials, Chosun University Graduate School, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 700 1- Lee Young-Min Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 700 1- Kang Joon Department of Internal Medicine, Mokpo Jung-ang General Hospital, Mokpo, Republic of Korea aut NATIONALLICENCE 700 1- Chae Seung Department of Internal Medicine, Mokpo Jung-ang General Hospital, Mokpo, Republic of Korea aut NATIONALLICENCE 700 1- Ki Young-Jae Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 700 1- Song Heesang Department of Biochemistry and Molecular Biology, Chosun University School of Medicine, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 700 1- Koh Young-Youp Department of Internal Medicine, Chosun University School of Medicine, 375 Seo-suk dong, Dong-Gu, 501-759, Gwangju, Republic of Korea aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/6(2015-11-01), 728-733 0910-8327 30:6<728 2015 30 380