caa a22 4500 606220801 CHVBK 20210128101125.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00380-014-0540-5 doi (NATIONALLICENCE)springer-10.1007/s00380-014-0540-5 Effects of the topographical extent of coronary artery ectasia on coronary blood flow in patients with aortic aneurysms [Elektronische Daten] [Hiroki Ikenaga, Satoshi Kurisu, Noriaki Watanabe, Takashi Shimonaga, Tadanao Higaki, Toshitaka Iwasaki, Hiroto Utsunomiya, Naoya Mitsuba, Ken Ishibashi, Yoshihiro Dohi, Katsuhiko Imai, Taijiro Sueda, Yasuki Kihara] Aortic aneurysms are associated with coronary artery ectasia (CAE). However, the relation between the extent of CAE and coronary blood flow in patients with aortic aneurysms is not fully understood. This study was undertaken to assess the angiographic characteristics and effects of the topographical extent of CAE on coronary blood flow in patients with aortic aneurysms. This study consisted of 93 consecutive patients with aortic aneurysms (AA group) and 79 patients without aortic aneurysms who had angiographically normal coronary arteries as the control group (Control group). Coronary flow velocity was determined using the thrombolysis in myocardial infarction frame count (TFC) and the topographical extent of CAE was assessed. In the AA group, 43 patients (46.2%) had significant coronary artery stenosis and 37 patients (40.2%) had diffuse CAE. TFC was significantly higher in the AA group than in the control group in all 3 coronary arteries. Furthermore, mean corrected TFC (CTFC) was significantly higher in the AA group than in the control group (40.1±10.7 vs. 25.8±6.5, p<0.001). In the AA group, mean CTFC in patients with diffuse CAE was significantly higher than that in patients with segmental CAE (50.2±8.7 vs. 33.6±5.2, p<0.001). The mean CTFC correlated positively with the topographical extent of CAE. Many patients with aortic aneurysms were accompanied with angiographic coronary artery stenosis and CAE. Furthermore, patients with aortic aneurysms had higher CTFC than those without aortic aneurysms and it was primarily driven by more frequent prevalence of diffuse CAE. Springer Japan, 2014 Aortic aneurysms nationallicence Coronary artery ectasia nationallicence Thrombolysis in myocardial infarction frame count nationallicence Ikenaga Hiroki Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Kurisu Satoshi Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Watanabe Noriaki Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Shimonaga Takashi Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Higaki Tadanao Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Iwasaki Toshitaka Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Utsunomiya Hiroto Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Mitsuba Naoya Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Ishibashi Ken Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Dohi Yoshihiro Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Imai Katsuhiko Department of Cardiovascular Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan aut Sueda Taijiro Department of Cardiovascular Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan aut Kihara Yasuki Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Heart and Vessels Springer Japan 30/6(2015-11-01), 712-718 0910-8327 30:6<712 2015 30 380 https://doi.org/10.1007/s00380-014-0540-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0540-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ikenaga Hiroki Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Kurisu Satoshi Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Watanabe Noriaki Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Shimonaga Takashi Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Higaki Tadanao Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Iwasaki Toshitaka Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Utsunomiya Hiroto Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Mitsuba Naoya Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Ishibashi Ken Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Dohi Yoshihiro Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Imai Katsuhiko Department of Cardiovascular Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan aut NATIONALLICENCE 700 1- Sueda Taijiro Department of Cardiovascular Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan aut NATIONALLICENCE 700 1- Kihara Yasuki Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/6(2015-11-01), 712-718 0910-8327 30:6<712 2015 30 380