caa a22 4500 606221239 CHVBK 20210128101128.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00380-014-0507-6 doi (NATIONALLICENCE)springer-10.1007/s00380-014-0507-6 Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia [Elektronische Daten] [Jun-ichi Suzuki, Norio Aoyama, Mieko Aoki, Yuko Tada, Kouji Wakayama, Hiroshi Akazawa, Kunihiro Shigematsu, Katsuyuki Hoshina, Yuichi Izumi, Issei Komuro, Tetsuro Miyata, Yasunobu Hirata, Mitsuaki Isobe] Although there is a link between periodontitis and cardiovascular disease (CVD), the influence of periodontitis on CVD is unclear. The aim of this study was to assess the relationship between periodontal bacterial burden and CVD. We studied 142 patients with tachyarrhythmia (TA) and 25 patients with abdominal aortic aneurysm (AAA). We examined periodontitis and the presence of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans and Prevotella intermedia in the patients' saliva and subgingival plaque using PCR. We also measured serum antibody titers against the pathogens using ELISA. We found that the patients with AAA had fewer remaining teeth (14.6±2.0 vs. 20.9±0.7, P<0.05) and deeper pocket depth (3.01±0.26 vs. 2.52±0.05mm, P<0.05) compared to the TA patients. The existence of each periodontal bacterium in their saliva or subgingival plaque and serum antibody titers was comparable between the two groups. Periodontitis may have a larger affect on aneurysm progression compared to arrhythmia. Springer Japan, 2014 Aneurysm nationallicence Antibody nationallicence Arrhythmia nationallicence Bacteria nationallicence Periodontal disease nationallicence Suzuki Jun-ichi Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo, 113-8655, Tokyo, Japan aut Aoyama Norio Department of Periodontology, Tokyo Medical and Dental University, Tokyo, Japan aut Aoki Mieko Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut Tada Yuko Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut Wakayama Kouji Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut Akazawa Hiroshi Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut Shigematsu Kunihiro Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut Hoshina Katsuyuki Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut Izumi Yuichi Department of Periodontology, Tokyo Medical and Dental University, Tokyo, Japan aut Komuro Issei Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut Miyata Tetsuro Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut Hirata Yasunobu Tokyo Teishin Hospital, Tokyo, Japan aut Isobe Mitsuaki Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan aut Heart and Vessels Springer Japan 30/4(2015-07-01), 498-502 0910-8327 30:4<498 2015 30 380 https://doi.org/10.1007/s00380-014-0507-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0507-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Suzuki Jun-ichi Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo, 113-8655, Tokyo, Japan aut NATIONALLICENCE 700 1- Aoyama Norio Department of Periodontology, Tokyo Medical and Dental University, Tokyo, Japan aut NATIONALLICENCE 700 1- Aoki Mieko Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Tada Yuko Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Wakayama Kouji Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Akazawa Hiroshi Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Shigematsu Kunihiro Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Hoshina Katsuyuki Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Izumi Yuichi Department of Periodontology, Tokyo Medical and Dental University, Tokyo, Japan aut NATIONALLICENCE 700 1- Komuro Issei Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Miyata Tetsuro Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Hirata Yasunobu Tokyo Teishin Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Isobe Mitsuaki Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/4(2015-07-01), 498-502 0910-8327 30:4<498 2015 30 380