caa a22 4500 606221379 CHVBK 20210128101128.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00380-014-0532-5 doi (NATIONALLICENCE)springer-10.1007/s00380-014-0532-5 Risk factors for rehospitalization in heart failure with preserved ejection fraction compared with reduced ejection fraction [Elektronische Daten] [Masahiko Setoguchi, Yuji Hashimoto, Taro Sasaoka, Takashi Ashikaga, Mitsuaki Isobe] Although there have been several studies regarding heart failure with preserved ejection fraction (HFpEF), investigations of the risk factors for readmission of Japanese patients with HFpEF remain scarce. Therefore, our goal was to identify the risk factors for readmission of Japanese patients with heart failure (HF), particularly those with HFpEF. We analyzed 310 patients who were hospitalized for the first time with HF. Preserved EF was defined EF ≥50%, and reduced EF (rEF) was EF <50%. The study endpoint was readmission for HF after discharge. Medical history, vital signs, electrocardiograms, chest radiographs, blood tests and echocardiograms were compared between patients with HFpEF and with HFrEF. Among the 142 patients who had HFpEF, 43 reached the endpoint within 1year. Multivariate analysis revealed depression (HR: 7.185), high brain natriuretic peptide (BNP) levels at discharge (HR: 1.003), and dilated inferior vena cava (HR: 1.100) as independent risk factors for readmission. In contrast, 39 of the 168 patients with HFrEF reached the endpoint. Risk factors for readmission of HFrEF patients were low sodium (HR: 0.856), high blood urea nitrogen (HR: 1.045), high BNP levels at discharge (HR: 1.003) and absence of beta-blocker prescription (HR: 0.395). In conclusion, our study suggests that the predictors of HF readmission differ between HFpEF and HFrEF patients. Springer Japan, 2014 Inferior vena cava nationallicence Depression nationallicence Heart failure with preserved ejection fraction nationallicence Readmission nationallicence Setoguchi Masahiko Department of Cardiology, Kameda General Hospital, Kamogawa, Japan aut Hashimoto Yuji Department of Cardiology, Kameda General Hospital, Kamogawa, Japan aut Sasaoka Taro Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan aut Ashikaga Takashi Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan aut Isobe Mitsuaki Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan aut Heart and Vessels Springer Japan 30/5(2015-09-01), 595-603 0910-8327 30:5<595 2015 30 380 https://doi.org/10.1007/s00380-014-0532-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0532-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Setoguchi Masahiko Department of Cardiology, Kameda General Hospital, Kamogawa, Japan aut NATIONALLICENCE 700 1- Hashimoto Yuji Department of Cardiology, Kameda General Hospital, Kamogawa, Japan aut NATIONALLICENCE 700 1- Sasaoka Taro Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan aut NATIONALLICENCE 700 1- Ashikaga Takashi Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan aut NATIONALLICENCE 700 1- Isobe Mitsuaki Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/5(2015-09-01), 595-603 0910-8327 30:5<595 2015 30 380