caa a22 4500 606221409 CHVBK 20210128101128.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00380-014-0537-0 doi (NATIONALLICENCE)springer-10.1007/s00380-014-0537-0 The cardiac blood supply-workload balance in children [Elektronische Daten] [Tomoaki Murakami, Atsuhito Takeda, Kohta Takei, Shigeru Tateno, Yasutaka Kawasoe, Koichiro Niwa] It is well known that the reflected pressure wave in small children returns earlier than that in adolescent. The reason of early return of the reflected pressure wave in infancy is their height. The short distance between heart and reflection point makes the reflected pressure wave returning to the heart earlier. In adult, the early return (during systole) of the reflected pressure wave means disadvantage to cardiac blood supply-workload balance. The purpose of this study was to clarify whether the early return of the reflected pressure wave in small children impairs the cardiac blood supply-workload balance. This study enrolled 37 small left-to-right shunt patients with normal aortic circulation below 15years of age. The aortic pressure waveform was recorded using a pressure sensor mounted catheter, and augmentation index and subendocardial viability ratio were calculated. The age of patients was 6.1±3.2years. The augmentation index was 8.7±14.3% and the index had a negative correlation with patients' age (r=−0.6243, p<0.0001). The subendocardial viability ratio, which means the cardiac blood supply-workload balance, was 0.92±0.14 and the index had a positive relationship with patients' age (r=0.6435, p<0.0001). The cardiac blood supply-workload balance gradually improves from infancy to young adulthood. One of the causes of the unfavorable cardiac blood supply-workload balance in infancy would be the accelerated aortic pressure wave reflection due to their short height. Springer Japan, 2014 Aging nationallicence Growth nationallicence Aortic function nationallicence Central hemodynamics nationallicence Murakami Tomoaki Department of Cardiology, Chiba Children's Hospital, 579-1 Heta-cho, Midori-ku, 266-0007, Chiba, Japan aut Takeda Atsuhito Department of Pediatrics, Hokkaido University, Graduate School of Medicine, Sapporo, Japan aut Takei Kohta Department of Pediatrics, Hokkaido University, Graduate School of Medicine, Sapporo, Japan aut Tateno Shigeru Department of Adult Congenital Heart Disease and Pediatric Cardiology, Chiba Cardiovascular Center, Chiba, Japan aut Kawasoe Yasutaka Department of Adult Congenital Heart Disease and Pediatric Cardiology, Chiba Cardiovascular Center, Chiba, Japan aut Niwa Koichiro Department of Adult Congenital Heart Disease and Pediatric Cardiology, Chiba Cardiovascular Center, Chiba, Japan aut Heart and Vessels Springer Japan 30/5(2015-09-01), 626-631 0910-8327 30:5<626 2015 30 380 https://doi.org/10.1007/s00380-014-0537-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0537-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murakami Tomoaki Department of Cardiology, Chiba Children's Hospital, 579-1 Heta-cho, Midori-ku, 266-0007, Chiba, Japan aut NATIONALLICENCE 700 1- Takeda Atsuhito Department of Pediatrics, Hokkaido University, Graduate School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Takei Kohta Department of Pediatrics, Hokkaido University, Graduate School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Tateno Shigeru Department of Adult Congenital Heart Disease and Pediatric Cardiology, Chiba Cardiovascular Center, Chiba, Japan aut NATIONALLICENCE 700 1- Kawasoe Yasutaka Department of Adult Congenital Heart Disease and Pediatric Cardiology, Chiba Cardiovascular Center, Chiba, Japan aut NATIONALLICENCE 700 1- Niwa Koichiro Department of Adult Congenital Heart Disease and Pediatric Cardiology, Chiba Cardiovascular Center, Chiba, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/5(2015-09-01), 626-631 0910-8327 30:5<626 2015 30 380