caa a22 4500 60622145X CHVBK 20210128101129.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00380-013-0461-8 doi (NATIONALLICENCE)springer-10.1007/s00380-013-0461-8 Seasonal variation in patients with acute heart failure: prognostic impact of admission in the summer [Elektronische Daten] [Yoshiya Yamamoto, Akihiro Shirakabe, Noritake Hata, Nobuaki Kobayashi, Takuro Shinada, Kazunori Tomita, Masanori Yamamoto, Masafumi Tsurumi, Masato Matsushita, Hirotake Okazaki, Shinya Yokoyama, Kuniya Asai, Kyoichi Mizuno, Wataru Shimizu] There have been few reports discussing the clinical significance of the season of admission of acute heart failure (AHF) patients. The data of 661 patients with AHF admitted to the intensive care unit were analyzed. Patients were assigned to a summer admission (Group-S, n=113, between July and September), a winter admission (Group-W, n=214, between December and February), or to the other seasons admission group (Group-O, n=334). We evaluated the relationships between the seasonal variations and the clinical profiles, and the long-term prognosis. There were significantly more patients with cardiomyopathy and New York Heart Association class 4, and the serum levels of total bilirubin were significantly higher in Group-S (85.8, 24.8%, and 0.60 [0.50-0.90]) than in Group-W (75.2, 15.4%, and 0.60 [0.40-0.78]). The left ventricular ejection fraction on admission was significantly reduced and intravenous administration of dobutamine was used more frequently in Group-S (30.0 [25.0-46.0], 31.9%) than in Group-W (34.4 [25.2-48.0], 20.6%) and Group-O (35.0 [25.0-46.0], 19.8%). The multivariate Cox regression model found that summer admission was independently associated with cardiovascular death (HR: 1.58, 95% CI 1.01-2.48; p=0.044) and heart failure (HF) events (HR: 1.55, 95% CI 1.05-2.28; p=0.028). The Kaplan-Meier curves showed that the cardiovascular death rate was significantly higher in Group-S than in Group-W and Group-O, and the HF events were significantly higher in Group-S than in Group-O. The summer admission AHF patients included sicker patients, and the prognosis in these patients was worse than in the patients admitted at other times. Springer Japan, 2014 Heart failure nationallicence Season nationallicence Clinical profiles nationallicence Epidemiologic methods nationallicence Prognosis nationallicence Yamamoto Yoshiya Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Shirakabe Akihiro Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Hata Noritake Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Kobayashi Nobuaki Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Shinada Takuro Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Tomita Kazunori Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Yamamoto Masanori Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Tsurumi Masafumi Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Matsushita Masato Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Okazaki Hirotake Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Yokoyama Shinya Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut Asai Kuniya Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan aut Mizuno Kyoichi Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan aut Shimizu Wataru Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan aut Heart and Vessels Springer Japan 30/2(2015-03-01), 193-203 0910-8327 30:2<193 2015 30 380 https://doi.org/10.1007/s00380-013-0461-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-013-0461-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yamamoto Yoshiya Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Shirakabe Akihiro Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Hata Noritake Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Kobayashi Nobuaki Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Shinada Takuro Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Tomita Kazunori Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Yamamoto Masanori Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Tsurumi Masafumi Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Matsushita Masato Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Okazaki Hirotake Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Yokoyama Shinya Division of Intensive Care Unit (ICU), Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, 270-1694, Inzai, Chiba, Japan aut NATIONALLICENCE 700 1- Asai Kuniya Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan aut NATIONALLICENCE 700 1- Mizuno Kyoichi Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan aut NATIONALLICENCE 700 1- Shimizu Wataru Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/2(2015-03-01), 193-203 0910-8327 30:2<193 2015 30 380