caa a22 4500 606221484 CHVBK 20210128101129.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00380-014-0471-1 doi (NATIONALLICENCE)springer-10.1007/s00380-014-0471-1 Evaluation of repolarization dynamics using the QT-RR regression line slope and intercept relationship during 24-h Holter ECG [Elektronische Daten] [Akira Fujiki, Ryozo Yoshioka, Masao Sakabe] QT-RR linear regression consists of two parameters, slope and intercept, and the aim of this study was to evaluate repolarization dynamics using the QT-RR linear regression slope and intercept relationship during 24-h Holter ECG. This study included 466 healthy subjects (54.6±14.6years; 200 men and 266 women) and 17 patients with ventricular arrhythmias, consisted of 10 patients with idiopathic ventricular fibrillation (IVF) and 7 patients with torsades de pointes (TDP). QT and RR intervals were measured from ECG waves based on a 15-s averaged ECG during 24-h Holter recording using an automatic QT analyzing system. The QT interval dependence on the RR interval was analyzed using a linear regression line for each subject ([QT]=A[RR]+B; where A is the slope and B is the y-intercept). The slope of the QT-RR regression line in healthy subjects was significantly greater in women than in men (0.185±0.036 vs. 0.161±0.033, p<0.001) and the intercept was significantly smaller in women than in men (0.229±0.028 vs. 0.240±0.027, p<0.001). A scatter diagram of the QT-RR regression line slope and intercept among healthy subjects demonstrated a statistically significant negative correlation (B=−0.62A+0.34, r=−0.79). Distribution of both scatter diagrams of the slope and the intercept of the QT-RR regression line in patients with IVF and TDP was different from healthy subjects (left corner for IVF and upward shift for TDP). The slope and intercept relationship of the QT-RR linear regression line based on 24-h Holter ECG may become a simple useful marker for abnormality of ventricular repolarization dynamics. Springer Japan, 2014 Idiopathic ventricular fibrillation nationallicence Long QT syndrome nationallicence QT interval nationallicence QT-RR relation nationallicence Torsades de pointes nationallicence Fujiki Akira Division of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi Aoiku, 420-0853, Shizuoka, Japan aut Yoshioka Ryozo Division of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi Aoiku, 420-0853, Shizuoka, Japan aut Sakabe Masao Division of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi Aoiku, 420-0853, Shizuoka, Japan aut Heart and Vessels Springer Japan 30/2(2015-03-01), 235-240 0910-8327 30:2<235 2015 30 380 https://doi.org/10.1007/s00380-014-0471-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0471-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fujiki Akira Division of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi Aoiku, 420-0853, Shizuoka, Japan aut NATIONALLICENCE 700 1- Yoshioka Ryozo Division of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi Aoiku, 420-0853, Shizuoka, Japan aut NATIONALLICENCE 700 1- Sakabe Masao Division of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi Aoiku, 420-0853, Shizuoka, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/2(2015-03-01), 235-240 0910-8327 30:2<235 2015 30 380