caa a22 4500 606221603 CHVBK 20210128101129.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00380-014-0474-y doi (NATIONALLICENCE)springer-10.1007/s00380-014-0474-y Prognostic implications of optimal medical therapy in patients undergoing percutaneous coronary intervention for acute coronary syndrome in octogenarians [Elektronische Daten] [Atsushi Anzai, Yuichiro Maekawa, Masaki Kodaira, Satoshi Mogi, Takahide Arai, Takashi Kawakami, Hideaki Kanazawa, Kentaro Hayashida, Shinsuke Yuasa, Akio Kawamura, Keiichi Fukuda] The proportion of elderly acute coronary syndrome (ACS) patients who receive optimal medical therapy (OMT) after percutaneous coronary intervention (PCI) and whether OMT affects their long-term outcomes remain unclear. We retrospectively investigated 405 ACS patients who underwent stent implantation between 2005 and 2009, and compared the outcomes between patients <80years of age vs. ≥80years of age. The prescription rate of the recommended medical agents for ACS in both groups during hospitalization and 2years after admission was also retrieved. Among the enrolled study population, 75 patients (19%) were aged ≥80years. These elderly patients had a higher 2-year mortality compared with patients aged <80years group. The prescription rate of beta-blockers, angiotensin-blocking drugs, and statins tended to be lower in patients aged ≥80years than in those aged <80years. Furthermore, among patients ≥80years of age, those who received OMT had better clinical outcome of 2-year mortality compared to those without OMT. Elderly patients with ACS treated by PCI are at substantially higher risk of adverse events than younger patients. However, they are less likely to receive OMT. PCI with OMT might improve the clinical outcomes of elderly ACS patients. Springer Japan, 2014 Optimal medical therapy nationallicence Acute coronary syndrome nationallicence Percutaneous coronary intervention nationallicence Octogenarians nationallicence Anzai Atsushi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Maekawa Yuichiro Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Kodaira Masaki Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Mogi Satoshi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Arai Takahide Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Kawakami Takashi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Kanazawa Hideaki Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Hayashida Kentaro Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Yuasa Shinsuke Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Kawamura Akio Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Fukuda Keiichi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut Heart and Vessels Springer Japan 30/2(2015-03-01), 186-192 0910-8327 30:2<186 2015 30 380 https://doi.org/10.1007/s00380-014-0474-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00380-014-0474-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Anzai Atsushi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Maekawa Yuichiro Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Kodaira Masaki Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Mogi Satoshi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Arai Takahide Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Kawakami Takashi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Kanazawa Hideaki Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Hayashida Kentaro Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Yuasa Shinsuke Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Kawamura Akio Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 700 1- Fukuda Keiichi Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, 160-8582, Tokyo, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer Japan 30/2(2015-03-01), 186-192 0910-8327 30:2<186 2015 30 380