caa a22 4500 606222057 CHVBK 20210128101131.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00038-015-0708-5 doi (NATIONALLICENCE)springer-10.1007/s00038-015-0708-5 Hepatitis C in key populations in Latin America and the Caribbean: systematic review and meta-analysis [Elektronische Daten] [Monica Alonso, Annika Gutzman, Rafael Mazin, Carlos Pinzon, Ludovic Reveiz, Massimo Ghidinelli] Objectives: Summarize hepatitis C virus (HCV) prevalence in injecting (IDU) and non-injecting drug users (NIDU), men who have sex with men (MSM), sex workers, and prison inmates in Latin America and the Caribbean (LAC). Methods: Systematic review on HCV prevalence in sub-populations in LAC. Databases searched from 1-1-2000 to 10-30-2013. Inclusion criteria: prevalence studies in sub-populations in LAC. HCV-antibody was marker for prevalence of current/past HCV infection and HCV-RNA for prevalence of HCV current infection. Results: IDU HCV current/past infection presented highest prevalence, from 1.7% in Colombia to over 95% in Ciudad Juarez and Tijuana, Mexico and pooled regional anti-HCV prevalence was 49% (CI 95% 22.6-76.3%). NIDU, MSM and sex workers anti-HCV prevalence was below 10%, and pooled regional prevalence of 4% (CI 95% 2.6-4.5%), 3% (CI 95% 1.7-4.5%) and 2% (CI 95% 1.0-3.4%), respectively. Prison inmates presented higher values, but prevalence decreased over the 15-year time span (p<0.001). Current HCV infection from three countries showed prevalence under 10% in prison inmates and 1-46% among drug users. Conclusions: Disease burden is high and surveillance, prevention and treatment should target these groups in LAC. The Author(s), 2015 Hepatitis C nationallicence Latin America nationallicence Caribbean nationallicence Drug users nationallicence Men who have sex with men nationallicence Prisoners nationallicence LAC : Latin America and the Caribbean nationallicence IDU : Injecting drug users nationallicence NIDU : Non-injecting drug users nationallicence MSM : Men who have sex with men nationallicence HCV : Hepatitis C virus nationallicence DU : Drug users nationallicence Alonso Monica Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut Gutzman Annika Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut Mazin Rafael Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut Pinzon Carlos Pan American Health Organization, Knowledge Management, Bioethics and Research, Washington, DC, USA aut Reveiz Ludovic Pan American Health Organization, Knowledge Management, Bioethics and Research, Washington, DC, USA aut Ghidinelli Massimo Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut International Journal of Public Health Springer Basel 60/7(2015-11-01), 789-798 1661-8556 60:7<789 2015 60 38 https://doi.org/10.1007/s00038-015-0708-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00038-015-0708-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Alonso Monica Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut NATIONALLICENCE 700 1- Gutzman Annika Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut NATIONALLICENCE 700 1- Mazin Rafael Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut NATIONALLICENCE 700 1- Pinzon Carlos Pan American Health Organization, Knowledge Management, Bioethics and Research, Washington, DC, USA aut NATIONALLICENCE 700 1- Reveiz Ludovic Pan American Health Organization, Knowledge Management, Bioethics and Research, Washington, DC, USA aut NATIONALLICENCE 700 1- Ghidinelli Massimo Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, 20037, Washington, DC, USA aut NATIONALLICENCE 773 0- International Journal of Public Health Springer Basel 60/7(2015-11-01), 789-798 1661-8556 60:7<789 2015 60 38