caa a22 4500 606222634 CHVBK 20210128101134.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00038-015-0679-6 doi (NATIONALLICENCE)springer-10.1007/s00038-015-0679-6 Mashhad stroke and heart atherosclerotic disorder (MASHAD) study: design, baseline characteristics and 10-year cardiovascular risk estimation [Elektronische Daten] [Majid Ghayour-Mobarhan, Mohsen Moohebati, Habibollah Esmaily, Mahmoud Ebrahimi, Seyed Parizadeh, Ali Heidari-Bakavoli, Mohammad Safarian, Naghmeh Mokhber, Mohsen Nematy, Hamidreza Saber, Maryam Mohammadi, Mohammad Andalibi, Gordon Ferns, Mahmoud Azarpazhooh] Objective: The Mashhad stroke and heart atherosclerotic disorder (MASHAD) study is a 10-year cohort study that aims to evaluate the impact of various genetic, environmental, nutritional and psychosocial risk factors on the incidence of cardiovascular events among an urban population in eastern Iran. Methods: The MASHAD study comprises a cohort of 9704 individuals aged 35-65years using a stratified cluster random sampling design. This cohort will be followed up until 2020, with follow-up examinations being undertaken every 3years. Ten-year cardiovascular disease (CVD) risk estimation was determined using NCEP ATP III criteria. Results: Overall, 88.4% of women and 79.2% of men (P<0.001) had at least one lipid abnormality. The 10-year risk for CVD of <10, 10-20 and >20% were observed to be 86.6, 11 and 2.5%, respectively. Predicted risk of CVD>10% using the Framingham algorithm was considerably higher in men compared to women. Overall, 9.5% [95% confidence interval (CI) 8.9-10.1%] of our subjects had prevalent CAD. Conclusion: The prevalence of CVD risk factors within our population is high compared to Western countries, indicating the necessity for interventional risk modifications. Swiss School of Public Health, 2015 Cardiovascular disease nationallicence Epidemiology nationallicence Risk factor nationallicence Metabolic syndrome nationallicence Iran nationallicence Ghayour-Mobarhan Majid Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Moohebati Mohsen Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Esmaily Habibollah Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Ebrahimi Mahmoud Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Parizadeh Seyed Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Heidari-Bakavoli Ali Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Safarian Mohammad Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Mokhber Naghmeh Psychiatry and Behavioral Research Center, Mashhad University of Medical Sciences, Mashhad, Iran aut Nematy Mohsen Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Saber Hamidreza Department of Epidemiology, Boston University School of Public Health, Boston, USA aut Mohammadi Maryam Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Andalibi Mohammad Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut Ferns Gordon Division of Medical Education, Brighton and Sussex Medical School, University of Brighton, Rm 342, Mayfield House, BN1 9PH, Brighton, UK aut Azarpazhooh Mahmoud Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut International Journal of Public Health Springer Basel 60/5(2015-07-01), 561-572 1661-8556 60:5<561 2015 60 38 https://doi.org/10.1007/s00038-015-0679-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00038-015-0679-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ghayour-Mobarhan Majid Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Moohebati Mohsen Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Esmaily Habibollah Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Ebrahimi Mahmoud Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Parizadeh Seyed Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Heidari-Bakavoli Ali Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Safarian Mohammad Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Mokhber Naghmeh Psychiatry and Behavioral Research Center, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Nematy Mohsen Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Saber Hamidreza Department of Epidemiology, Boston University School of Public Health, Boston, USA aut NATIONALLICENCE 700 1- Mohammadi Maryam Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Andalibi Mohammad Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 700 1- Ferns Gordon Division of Medical Education, Brighton and Sussex Medical School, University of Brighton, Rm 342, Mayfield House, BN1 9PH, Brighton, UK aut NATIONALLICENCE 700 1- Azarpazhooh Mahmoud Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran aut NATIONALLICENCE 773 0- International Journal of Public Health Springer Basel 60/5(2015-07-01), 561-572 1661-8556 60:5<561 2015 60 38