caa a22 4500 606230440 CHVBK 20210128101214.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10695-015-0088-z doi (NATIONALLICENCE)springer-10.1007/s10695-015-0088-z Dietary Aloe vera improves plasma lipid profile, antioxidant, and hepatoprotective enzyme activities in GIFT-tilapia ( Oreochromis niloticus ) after Streptococcus iniae challenge [Elektronische Daten] [Ndakalimwe Gabriel, Jun Qiang, Xin Ma, Jie He, Pao Xu, Kai Liu] The current study investigated the effects of dietary Aloe vera on plasma lipid profile status, antioxidant, and hepatoprotective enzyme activities of GIFT-tilapia juveniles under Streptococcus iniae challenge. Five dietary groups were designed including a control and 100% Aloe powder incorporated into a tilapia feed at 0.5, 1, 2, and 4%/kg feed, which were administered for 8weeks. Fish fed dietary Aloe at 4%/kg feed significantly reduced in total cholesterol, while triacylglycerol reduced (P<0.05) in those fed 0.5, 2, and 4% Aloe/kg feed compared to unsupplemented ones. High-density lipoprotein was significantly elevated in fish fed 0.5 and 1% Aloe/kg feed compared to unsupplemented ones, and no significant changes (P>0.05) were noted in low-density lipoprotein among test groups. Furthermore, high activities of superoxide dismutase, catalase, and glutathione peroxide in liver tissues were observed in Aloe-supplemented fish compared to unsupplemented ones, before and after S. iniae challenge (7.7×106CFUcells/mL). Variations were also noted in malondialdehyde activity throughout the trial, but no significant difference (P>0.05) was observed between groups. Meanwhile, Aloe-supplemented fish reduced serum aspartate and alanine aminotransferase (AST and ALT) activities before and after challenge. Based on the second-order polynomial regression analysis, dietary Aloe inclusion levels less than or equal to 1.88, 1.86, and 2.79%/kg feed were determined to be suitable in improving plasma lipid profile status, antioxidant, and hepatoprotective enzyme activities in GIFT-tilapia in this study, respectively. Thus, A. vera extracts may be recommended as a tilapia feed supplement to enhance fish antioxidant and hepatoprotective capacities, especially during disease outbreaks. Springer Science+Business Media Dordrecht, 2015 Aloe vera nationallicence Antioxidative stress nationallicence Aquaculture nationallicence Streptococcus nationallicence Tilapia nationallicence Gabriel Ndakalimwe Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut Qiang Jun Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut Ma Xin Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut He Jie Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut Xu Pao Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut Liu Kai Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut Fish Physiology and Biochemistry Springer Netherlands 41/5(2015-10-01), 1321-1332 0920-1742 41:5<1321 2015 41 10695 https://doi.org/10.1007/s10695-015-0088-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10695-015-0088-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gabriel Ndakalimwe Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut NATIONALLICENCE 700 1- Qiang Jun Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut NATIONALLICENCE 700 1- Ma Xin Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut NATIONALLICENCE 700 1- He Jie Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut NATIONALLICENCE 700 1- Xu Pao Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut NATIONALLICENCE 700 1- Liu Kai Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, China aut NATIONALLICENCE 773 0- Fish Physiology and Biochemistry Springer Netherlands 41/5(2015-10-01), 1321-1332 0920-1742 41:5<1321 2015 41 10695