caa a22 4500 60623277X CHVBK 20210128101228.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10508-014-0279-1 doi (NATIONALLICENCE)springer-10.1007/s10508-014-0279-1 Depression and Sexual Dysfunction Among HIV-Positive and HIV-Negative Men Who Have Sex With Men: Mediation by Use of Antidepressants and Recreational Stimulants [Elektronische Daten] [Trevor Hart, Brian Mustanski, Daniel Ryan, Pamina Gorbach, Ron Stall, Pamela Surkan, Michael Plankey] Erectile dysfunction and other forms of sexual dysfunction are highly prevalent among HIV+ men who have sex with men (MSM). Research has not previously identified the mechanisms by which depression may be associated with sexual dysfunction among HIV-positive and HIV-seronegative (HIV-negative) MSM. The present study examined the role of antidepressant use, stimulant use, and smoking as mediators of the relation between depression and sexual dysfunction among HIV-positive and HIV-negative MSM. Participants enrolled in the Multicenter AIDS Cohort Study, an ongoing prospective study of the natural and treated histories of HIV infection among MSM in the United States, completed a modified version of the International Index of Erectile Function for MSM. The study sample included 1,363 participants, with 619 HIV-positive men and 744 HIV-negative men. A structural equation model examined depression as a predictor of subsequent sexual dysfunction, mediated by antidepressant use, stimulant use, and smoking. Depression predicted subsequent sexual function among both HIV-negative and HIV-positive MSM. This effect appeared to be both a direct effect and an indirect effect via antidepressant use. Findings suggest that antidepressant medication use may partially explain sexual dysfunction among MSM. Springer Science+Business Media New York, 2014 Depression nationallicence Sexual dysfunction nationallicence SSRIs nationallicence Men who have sex with men nationallicence Erectile dysfunction nationallicence Sexual orientation nationallicence Hart Trevor Department of Psychology, Ryerson University, 350 Victoria St., M5B 2K3, Toronto, ON, Canada aut Mustanski Brian Department of Medical Social Sciences, Northwestern University, Chicago, IL, USA aut Ryan Daniel Department of Medical Social Sciences, Northwestern University, Chicago, IL, USA aut Gorbach Pamina Department of Epidemiology, University of California, Los Angeles, Los Angeles, CA, USA aut Stall Ron Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA, USA aut Surkan Pamela School of Public Health, Johns Hopkins University, Baltimore, MD, USA aut Plankey Michael School of Medicine Division of Infectious Diseases, Georgetown University, Washington, DC, USA aut Archives of Sexual Behavior Springer US; http://www.springer-ny.com 44/2(2015-02-01), 399-409 0004-0002 44:2<399 2015 44 10508 https://doi.org/10.1007/s10508-014-0279-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10508-014-0279-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hart Trevor Department of Psychology, Ryerson University, 350 Victoria St., M5B 2K3, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Mustanski Brian Department of Medical Social Sciences, Northwestern University, Chicago, IL, USA aut NATIONALLICENCE 700 1- Ryan Daniel Department of Medical Social Sciences, Northwestern University, Chicago, IL, USA aut NATIONALLICENCE 700 1- Gorbach Pamina Department of Epidemiology, University of California, Los Angeles, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Stall Ron Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA, USA aut NATIONALLICENCE 700 1- Surkan Pamela School of Public Health, Johns Hopkins University, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Plankey Michael School of Medicine Division of Infectious Diseases, Georgetown University, Washington, DC, USA aut NATIONALLICENCE 773 0- Archives of Sexual Behavior Springer US; http://www.springer-ny.com 44/2(2015-02-01), 399-409 0004-0002 44:2<399 2015 44 10508