caa a22 4500 606238875 CHVBK 20210128101300.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10862-015-9492-z doi (NATIONALLICENCE)springer-10.1007/s10862-015-9492-z An fMRI Pilot Study of Cognitive Reappraisal in Children: Divergent Effects on Brain and Behavior [Elektronische Daten] [Lea Dougherty, Sarah Blankenship, Philip Spechler, Srikanth Padmala, Luiz Pessoa] Although neuroimaging studies in adults demonstrate that cognitive reappraisal effectively down-regulates negative affect and results in increased prefrontal and decreased amygdala activity, very limited empirical data exist on the neural basis of cognitive reappraisal in children. This study aimed to pilot test a developmentally-appropriate guided cognitive reappraisal task in order to examine the effects of cognitive reappraisal on children's self-reports of affect and brain responses. Study 1 (N = 19, 4-10years-old) found that children successfully employed guided cognitive reappraisal to decrease subjective ratings of negative affect, supporting the effectiveness of the guided cognitive reappraisal task. Study 2 (N = 15, ages 6-10years-old) investigated the neural responses to guided cognitive reappraisal and found that the neural responses showed increased activation in the amygdala and ventromedial prefrontal cortex during the cognitive reappraisal condition compared to the no regulation condition. In addition, amygdala activity was positively correlated with ventromedial prefrontal cortex activation during cognitive reappraisal. Findings suggest that the neural networks supporting cognitive reappraisal in children involve similar brain regions but brain responses deviate from findings in adults. Our findings suggest that the neural networks supporting emotion regulation are still developing during middle childhood, and future research is necessary to delineate age-related development of the neural network involved in cognitive reappraisal. Springer Science+Business Media New York, 2015 Emotion regulation nationallicence Cognitive reappraisal nationallicence Children nationallicence fMRI nationallicence Amygdala nationallicence Prefrontal cortex nationallicence Dougherty Lea Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut Blankenship Sarah Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut Spechler Philip Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut Padmala Srikanth Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut Pessoa Luiz Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut Journal of Psychopathology and Behavioral Assessment Springer US; http://www.springer-ny.com 37/4(2015-12-01), 634-644 0882-2689 37:4<634 2015 37 10862 https://doi.org/10.1007/s10862-015-9492-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10862-015-9492-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dougherty Lea Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut NATIONALLICENCE 700 1- Blankenship Sarah Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut NATIONALLICENCE 700 1- Spechler Philip Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut NATIONALLICENCE 700 1- Padmala Srikanth Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut NATIONALLICENCE 700 1- Pessoa Luiz Department of Psychology, University of Maryland, 20742, College Park, MD, USA aut NATIONALLICENCE 773 0- Journal of Psychopathology and Behavioral Assessment Springer US; http://www.springer-ny.com 37/4(2015-12-01), 634-644 0882-2689 37:4<634 2015 37 10862