caa a22 4500 606239898 CHVBK 20210128101305.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00508-015-0709-7 doi (NATIONALLICENCE)springer-10.1007/s00508-015-0709-7 Diffusion-weighted MRI in the differential diagnosis of uterine endometrial cavity tumors [Elektronische Daten] [Omer Karakas, Ekrem Karakas, Ferit Dogan, Nihat Kilicaslan, Aysun Camuzcuoglu, Adnan Incebiyik, Hakan Camuzcuoglu] Summary: Background: This study aimed to investigate the efficacy of quantitative apparent diffusion coefficient (ADC) measurement in the differential diagnosis of the uterine endometrial cavity tumors (UECT). Methods: This study included consecutive 36 female patients with UECT. The groups were formed as follows: group 1, patients with endometrial carcinoma; group 2, patients with endometrial polyp; group 3, patients with submucosal leiomyoma; and additionally group A, patients with malignant lesion; group B patients with benign lesion. Tumoral and outer myometrial ADC values were measured and the tumor-myometrium ADC ratios were calculated in all patients. Kolmogorov-Smirnov tests were used to test the normality of the data distributions. The data were not normally distributed, and therefore, nonparametric tests were performed. The cut-off values, sensitivity, and specificity were determined by the receiver operating characteristic analysis. Results: The mean ADC value and ratio of group 1 were lower than that of group 2 and 3, and the mean ADC value and ratio of group 3 were lower than that of group 2. The sensitivity and specificity for group 1, 2, and 3 were as follows: 90, 100, and 66.7%; and 81.8, 88, and 58.8%, respectively, in terms of the ADC values; 90, 100 and 67%; and 77.3, 96, and 64.7% in terms of the ADC ratios. Statistically significant differences were demonstrated between group A and B in terms of mean tumoral ADC values and ratios. Sensitivity and specificity were found to be 90 and 81.8%, respectively, in terms of the ADC values. The sensitivity and specificity were found to be 90 and 77.3%, respectively, in terms of the ADC ratios. Conclusions: ADC values and ratios represent a promising parameter in the determination of the tumoral lesions in patients with UECT. Springer-Verlag Wien, 2015 Diffusion-weighted magnetic resonance imaging nationallicence Neoplasm nationallicence Uterus nationallicence Karakas Omer Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut Karakas Ekrem Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut Dogan Ferit Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut Kilicaslan Nihat Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut Camuzcuoglu Aysun Faculty of Medicine, Department of Obstetrics and Gynecology, Harran University, Sanliurfa, Turkey aut Incebiyik Adnan Faculty of Medicine, Department of Obstetrics and Gynecology, Harran University, Sanliurfa, Turkey aut Camuzcuoglu Hakan Faculty of Medicine, Department of Obstetrics and Gynecology, Harran University, Sanliurfa, Turkey aut Wiener klinische Wochenschrift Springer Vienna 127/7-8(2015-04-01), 266-273 0043-5325 127:7-8<266 2015 127 508 https://doi.org/10.1007/s00508-015-0709-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00508-015-0709-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Karakas Omer Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut NATIONALLICENCE 700 1- Karakas Ekrem Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut NATIONALLICENCE 700 1- Dogan Ferit Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut NATIONALLICENCE 700 1- Kilicaslan Nihat Faculty of Medicine, Department of Radiology, Harran University, Yenisehir Campus, 63300, Sanliurfa, Turkey aut NATIONALLICENCE 700 1- Camuzcuoglu Aysun Faculty of Medicine, Department of Obstetrics and Gynecology, Harran University, Sanliurfa, Turkey aut NATIONALLICENCE 700 1- Incebiyik Adnan Faculty of Medicine, Department of Obstetrics and Gynecology, Harran University, Sanliurfa, Turkey aut NATIONALLICENCE 700 1- Camuzcuoglu Hakan Faculty of Medicine, Department of Obstetrics and Gynecology, Harran University, Sanliurfa, Turkey aut NATIONALLICENCE 773 0- Wiener klinische Wochenschrift Springer Vienna 127/7-8(2015-04-01), 266-273 0043-5325 127:7-8<266 2015 127 508