caa a22 4500 606240144 CHVBK 20210128101306.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00508-015-0817-4 doi (NATIONALLICENCE)springer-10.1007/s00508-015-0817-4 Assessment of left atrial volume and function in patients with psoriasis by using real time three-dimensional echocardiography [Elektronische Daten] [Halil Atas, Alper Kepez, Mehmet Bozbay, Dilek Seckin Gencosmanoglu, Altug Cincin, Murat Sunbul, Ayfer Yildiz Bozbay, Ramila Darvishova, Tulin Ergun] Summary: Background: Left atrial (LA) volume has been identified as a predictor of adverse cardiovascular outcomes, both in the general population and in selected clinical conditions. The aim of this study was to evaluate the effect of psoriasis on LA volume and mechanical function. Methods: A total of 40 consecutive normotensive psoriasis patients free of any cardiovascular disease and 39 healthy volunteers were included. All participants underwent comprehensive transthoracic echocardiographic examination. LA volume and mechanical function were evaluated using real-time three-dimensional echocardiography (RT3DE). Results: There were no significant differences between psoriasis and control groups with regard to conventional echocardiographic parameters. Individuals with psoriasis had a higher incidence of left ventricular diastolic dysfunction (LVDD) than the controls; nine people with psoriasis (23 %) and three control individuals (8 %) had LVDD (p = 0.06). With regard to the parameters obtained from RT3DE, LA maximum, LA minimum, passive stroke volume, and passive emptying fraction were significantly higher; whereas LA active emptying fraction, LA total emptying fraction, LA expansion index, and active stroke volume values were significantly lower in individuals with psoriasis compared with controls. Disease duration and Psoriasis Area of Severity Index (PASI) score correlated with the majority of volume parameters. Conclusion: Individuals with psoriasis had higher LA phasic volumes and impaired LA mechanical function compared with healthy controls. LA volume and functional analysis with RT3DE may facilitate recognition of subtle LA dysfunction in patients with psoriasis. Springer-Verlag Wien, 2015 Psoriasis nationallicence Real-time three-dimensional echocardiography nationallicence Left atrial volume nationallicence Left atrial mechanical function nationallicence Left atrial contractility nationallicence Atas Halil Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Kepez Alper Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Bozbay Mehmet Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Gencosmanoglu Dilek Seckin Department of Dermatology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Cincin Altug Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Sunbul Murat Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Bozbay Ayfer Yildiz Faculty of Medicine Hospital, Department of Dermatology, Fatih University, Istanbul, Turkey aut Darvishova Ramila Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Ergun Tulin Department of Dermatology, Marmara University Training and Research Hospital, Istanbul, Turkey aut Wiener klinische Wochenschrift Springer Vienna 127/21-22(2015-11-01), 858-863 0043-5325 127:21-22<858 2015 127 508 https://doi.org/10.1007/s00508-015-0817-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00508-015-0817-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Atas Halil Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Kepez Alper Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Bozbay Mehmet Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Gencosmanoglu Dilek Seckin Department of Dermatology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Cincin Altug Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Sunbul Murat Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Bozbay Ayfer Yildiz Faculty of Medicine Hospital, Department of Dermatology, Fatih University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Darvishova Ramila Department of Cardiology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Ergun Tulin Department of Dermatology, Marmara University Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 773 0- Wiener klinische Wochenschrift Springer Vienna 127/21-22(2015-11-01), 858-863 0043-5325 127:21-22<858 2015 127 508