caa a22 4500 606240594 CHVBK 20210128101309.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00508-015-0750-6 doi (NATIONALLICENCE)springer-10.1007/s00508-015-0750-6 Vision problems in Down syndrome adults do not hamper communication, daily living skills and socialisation [Elektronische Daten] [Anastasia Dressler, Margherita Bozza, Valentina Perelli, Francesca Tinelli, Andrea Guzzetta, Giovanni Cioni, Stefania Bargagna] Summary: Background: Down syndrome is the most commonly occurring chromosomal condition with a prevalence of 11.2-10000 life-births in Europe. The most important concern consists of various degrees of intellectual disability and sensory deficits. The overall prevalence of ophthalmologic abnormalities has been reported to be as high as 46-100%. Impairment of vision potentially hampers the capacity of learning and communication and thus of social integration. The aim of our study is to assess prospectively the occurrence of vision problems in patients with DS with special emphasis on adaptive behaviour and cognition. Methods: Assessments included Hirschberg's corneal reflex method, eye alignment, cover test, Vineland Adaptive Behaviour Scales (VABS) for adaptive behaviour and Coloured Progressive Matrices (CPM) for cognitive abilities. Results: We included prospectively 49 individuals from 19-52 years. Ophthalmologic problems were observed in 81.6% of our DS patients. The total number of visual disorders and symptoms was equally distributed with respect to ID-group and to levels of adaptive behaviour (p>0.050). When comparing individuals matched for age, gender, cognitive skills and sociocultural background in a subset of individuals, vision problems did not decrease adaptive behaviour skills of our patients with visual disorders and daily living skills even fared better (p=0.046). Conclusions: Effective early correction and intervention on visual-motor deficits seem to be important, but nevertheless personal autonomy is not seriously detained. Springer-Verlag Wien, 2015 Vision problems nationallicence Down syndrome nationallicence Adaptive behaviour nationallicence Daily living skills nationallicence Cognitive abilities nationallicence Dressler Anastasia Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut Bozza Margherita IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut Perelli Valentina IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut Tinelli Francesca IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut Guzzetta Andrea IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut Cioni Giovanni IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut Bargagna Stefania IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut Wiener klinische Wochenschrift Springer Vienna 127/15-16(2015-08-01), 594-600 0043-5325 127:15-16<594 2015 127 508 https://doi.org/10.1007/s00508-015-0750-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00508-015-0750-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dressler Anastasia Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut NATIONALLICENCE 700 1- Bozza Margherita IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut NATIONALLICENCE 700 1- Perelli Valentina IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut NATIONALLICENCE 700 1- Tinelli Francesca IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut NATIONALLICENCE 700 1- Guzzetta Andrea IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut NATIONALLICENCE 700 1- Cioni Giovanni IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut NATIONALLICENCE 700 1- Bargagna Stefania IRCCS, Stella Maris Foundation, Scientific Institute for Child and Adolescence Neurology and Psychiatry, University Pisa, Italy, Europe aut NATIONALLICENCE 773 0- Wiener klinische Wochenschrift Springer Vienna 127/15-16(2015-08-01), 594-600 0043-5325 127:15-16<594 2015 127 508