caa a22 4500 606240780 CHVBK 20210128101309.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00508-014-0626-1 doi (NATIONALLICENCE)springer-10.1007/s00508-014-0626-1 Self-reported frequency and impact of hypoglycaemic events in insulin-treated diabetic patients in Austria [Elektronische Daten] [Raimund Weitgasser, Sandra Lopes] Häufigkeit und Auswirkung von Hypoglykämien bei insulinbehandelten Diabetes-Patienten in Österreich Background: Hypoglycaemia is a common side effect of insulin therapy and presents a barrier to diabetes management, however, limited data exist on the real-world frequency of events. We investigated the self-reported rates of non-severe and severe hypoglycaemic events in Austria. We also explored hypoglycaemia awareness, patient-physician communication and the health-related and economic impact of events. Methods: People with Type-1 or insulin-treated Type-2 diabetes >15 years of age completed up to 4 questionnaires (weekly intervals). Non-severe hypoglycaemic events were defined by requiring no assistance while severe hypoglycaemic events need help from a third party. Results: Overall, 553 respondents (40% Type-1, 60% Type-2) enrolled, providing a total of 1,773 patient-weeks. The mean annual non-severe event frequencies were 85 for Type-1 and 15-28 for Type-2 (depending on insulin regimen). In respondents who experienced ≥1 non-severe event in the study period, annual rates were 18% higher in Type-1 and 77% higher in Type-2. The proportion of respondents reporting ‘awareness' of hypoglycaemic symptoms was 48% for Type-1 and 43-61% for Type-2 respondents. The proportion of respondents who rarely/never inform their physician of hypoglycaemic events was 67% (Type-1) and 43-53% (Type-2). The most commonly reported health-related impacts were tiredness/fatigue (58% of events) and reduced alertness (41% of events). Conclusion: Non-severe hypoglycaemic events are common in Type-1 and insulin-treated Type-2 diabetes patients in Austria. There may be subgroups of patients who are predisposed to higher rates of non-severe events. Even non-severe events have a negative impact on physical and emotional well-being. The Author(s), 2014 Diabetes mellitus nationallicence Hypoglycaemia nationallicence Insulin nationallicence Quality of life nationallicence Hypoglykämie nationallicence Lebensqualität nationallicence Weitgasser Raimund Department of Internal Medicine, Diakonissen Hospital Salzburg, Salzburg, Austria aut Lopes Sandra Novo Nordisk Scandinavia AB, Region Danmark, Arne Jacobsens Allé 17, 9. sal, 2300, Copenhagen, Denmark aut Wiener klinische Wochenschrift Springer Vienna 127/1-2(2015-01-01), 36-44 0043-5325 127:1-2<36 2015 127 508 https://doi.org/10.1007/s00508-014-0626-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00508-014-0626-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Weitgasser Raimund Department of Internal Medicine, Diakonissen Hospital Salzburg, Salzburg, Austria aut NATIONALLICENCE 700 1- Lopes Sandra Novo Nordisk Scandinavia AB, Region Danmark, Arne Jacobsens Allé 17, 9. sal, 2300, Copenhagen, Denmark aut NATIONALLICENCE 773 0- Wiener klinische Wochenschrift Springer Vienna 127/1-2(2015-01-01), 36-44 0043-5325 127:1-2<36 2015 127 508