caa a22 4500 606240926 CHVBK 20210128101310.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00508-014-0653-y doi (NATIONALLICENCE)springer-10.1007/s00508-014-0653-y Delayed auditory pathway maturation and prematurity [Elektronische Daten] [Martin Koenighofer, Thomas Parzefall, Reinhard Ramsebner, Trevor Lucas, Klemens Frei] Verzögerte Hörbahnreifung und Frühgeburtlichkeit Summary: Background: Hearing loss is the most common sensory disorder in developed countries and leads to a severe reduction in quality of life. In this uncontrolled case series, we evaluated the auditory development in patients suffering from congenital nonsyndromic hearing impairment related to preterm birth. Methods: Six patients delivered preterm (25th-35th gestational weeks) suffering from mild to profound congenital nonsyndromic hearing impairment, descending from healthy, nonconsanguineous parents and were evaluated by otoacoustic emissions, tympanometry, brainstem-evoked response audiometry, and genetic testing. All patients were treated with hearing aids, and one patient required cochlear implantation. Results: One preterm infant (32nd gestational week) initially presented with a 70 dB hearing loss, accompanied by negative otoacoustic emissions and normal tympanometric findings. The patient was treated with hearing aids and displayed a gradual improvement in bilateral hearing that completely normalized by 14 months of age accompanied by the development of otoacoustic emission responses. Conclusions We present here for the first time a fully documented preterm patient with delayed auditory pathway maturation and normalization of hearing within 14 months of birth. Although rare, postpartum development of the auditory system should, therefore, be considered in the initial stages for treating preterm hearing impaired patients. Springer-Verlag Wien, 2014 Hearing loss nationallicence Sensorineural nationallicence Neonatal screening nationallicence Auditory pathways nationallicence Premature nationallicence Schwerhörigkeit nationallicence Neugeborenenscreening nationallicence Hörbahn nationallicence Frühgeburt nationallicence Koenighofer Martin Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut Parzefall Thomas Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut Ramsebner Reinhard Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut Lucas Trevor Center of Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria aut Frei Klemens Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut Wiener klinische Wochenschrift Springer Vienna 127/11-12(2015-06-01), 440-444 0043-5325 127:11-12<440 2015 127 508 https://doi.org/10.1007/s00508-014-0653-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00508-014-0653-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koenighofer Martin Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut NATIONALLICENCE 700 1- Parzefall Thomas Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut NATIONALLICENCE 700 1- Ramsebner Reinhard Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut NATIONALLICENCE 700 1- Lucas Trevor Center of Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria aut NATIONALLICENCE 700 1- Frei Klemens Department of Otorhinolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria aut NATIONALLICENCE 773 0- Wiener klinische Wochenschrift Springer Vienna 127/11-12(2015-06-01), 440-444 0043-5325 127:11-12<440 2015 127 508