caa a22 4500 606241213 CHVBK 20210128101312.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00508-015-0825-4 doi (NATIONALLICENCE)springer-10.1007/s00508-015-0825-4 Description of five dirofilariasis cases in South Hungary and review epidemiology of this disease for the country [Elektronische Daten] [Ilona Dóczi, László Bereczki, Tamás Gyetvai, Imre Fejes, Ákos Skribek, Áron Szabó, Szilvia Berkes, László Tiszlavicz, Noémi Bartha, Balázs Bende, Erika Kis, István Kucsera] Summary: Background: Dirofilariasis is an emerging zoonosis (supported by climate change) in Central Europe. Human infections are usually caused by Dirofilaria repens and Dirofilaria immitis with mediation of mosquito vectors. Aims of this publication were to report our dirofilariasis cases, and to summarize Hungarian epidemiological data by reviewing literature. Methods and results: We present five (four ophthalomological, one subcutaneous) cases observed within a 2-year period in Southern Hungary. Ages of infected patients were between 31 and 74 years. First case during pregnancy is also reported. There was no travel history in the anamnesis of patients which could explain acquisition of the infection. Moving, intact worms eliminated by surgical interventions were identified on the basis of morphological features as D. repens. Since the first report of human case, 115 further episodes (in addition to ours) were diagnosed in Hungary. Mean age of the patients was 47 years. Reviewing national reports, the ratio of subcutaneous infections was higher than that of the ocular ones (66 and 45, respectively). Evaluation of the territorial distribution of human episodes revealed that most infections occurred in patients living in the Danube-Tisza interfluvial region and eastern part of the country. However, sporadic cases were also found in western counties during 2014. Conclusion: Most of the Hungarian dirofilariasis cases were autochthonous infections. Occurrence in the western counties may suggest the spreading of this emerging zoonosis to these areas. Comprehensive monitoring and data analysis are desirable, therefore reporting the epidemiologic data in the case of human infections should be made mandatory. Springer-Verlag Wien, 2015 Dirofilaria repens nationallicence Epidemiology nationallicence Case report nationallicence Pregnancy nationallicence Hungary nationallicence Dóczi Ilona Faculty of Medicine, Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, 6 Semmelweis str, 6725, Szeged, Hungary aut Bereczki László Faculty of Medicine, Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, 6 Semmelweis str, 6725, Szeged, Hungary aut Gyetvai Tamás Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Fejes Imre Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Skribek Ákos Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Szabó Áron Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Berkes Szilvia Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Tiszlavicz László Faculty of Medicine, Department of Pathology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Bartha Noémi Faculty of Medicine, Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, 6 Semmelweis str, 6725, Szeged, Hungary aut Bende Balázs Faculty of Medicine, Department of Dermatology and Allergology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Kis Erika Faculty of Medicine, Department of Dermatology and Allergology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut Kucsera István National Center for Epidemiology, Budapest, Hungary aut Wiener klinische Wochenschrift Springer Vienna 127/17-18(2015-09-01), 696-702 0043-5325 127:17-18<696 2015 127 508 https://doi.org/10.1007/s00508-015-0825-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00508-015-0825-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dóczi Ilona Faculty of Medicine, Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, 6 Semmelweis str, 6725, Szeged, Hungary aut NATIONALLICENCE 700 1- Bereczki László Faculty of Medicine, Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, 6 Semmelweis str, 6725, Szeged, Hungary aut NATIONALLICENCE 700 1- Gyetvai Tamás Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Fejes Imre Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Skribek Ákos Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Szabó Áron Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Berkes Szilvia Faculty of Medicine, Department of Ophthalmology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Tiszlavicz László Faculty of Medicine, Department of Pathology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Bartha Noémi Faculty of Medicine, Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, University of Szeged, 6 Semmelweis str, 6725, Szeged, Hungary aut NATIONALLICENCE 700 1- Bende Balázs Faculty of Medicine, Department of Dermatology and Allergology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Kis Erika Faculty of Medicine, Department of Dermatology and Allergology, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary aut NATIONALLICENCE 700 1- Kucsera István National Center for Epidemiology, Budapest, Hungary aut NATIONALLICENCE 773 0- Wiener klinische Wochenschrift Springer Vienna 127/17-18(2015-09-01), 696-702 0043-5325 127:17-18<696 2015 127 508