caa a22 4500 60624249X CHVBK 20210128101319.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s12602-014-9175-1 doi (NATIONALLICENCE)springer-10.1007/s12602-014-9175-1 Immune Response of Salmonella Challenged Broiler Chickens Fed Diets Containing Gallipro®, a Bacillus subtilis Probiotic [Elektronische Daten] [Ali Sadeghi, Parvin Shawrang, Shirin Shakorzadeh] This study was conducted to investigate the effect of feeding a probiotic, Bacillus subtilis, on antibody titers against Newcastle and infectious bursal viruses in broiler chickens challenged with Salmonella enterica serotype Enteritidis. One hundred and sixty 1-day-old broiler chicks were randomly assigned to four treatments in a completely randomized design. The treatments were negative control, probiotic-treated group, challenged group, and challenged probiotic treated group. Salmonella challenging decreased (P<0.05) the relative weights of spleen and bursa. Inclusion of probiotic to diet of challenged chickens increased the relative weight of spleen, but had no effect on the relative weight of bursa. There were no differences for the antibody titers of chickens between negative control and probiotic-treated group. Salmonella challenging decreased (P<0.05) antibody titers against Newcastle and infectious bursal viruses. Improvements in the antibody titers were observed by the addition of probiotic to diet of these chickens. The results showed that dietary inclusion of probiotic had no significant effect on immune parameters of chickens at non-contaminated environment, display a greater efficacy at environment contaminated with pathogen and can improve immune responses of infected chickens. Springer Science+Business Media New York, 2014 Probiotics nationallicence Bacillus subtilis nationallicence Immune organ nationallicence Pathogen challenge nationallicence Immune cells profile nationallicence Sadeghi Ali Department of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran aut Shawrang Parvin Nuclear Agriculture Research School, Nuclear Science and Technology Research Institute, AEOI, Karaj, Iran aut Shakorzadeh Shirin Department of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran aut Probiotics and Antimicrobial Proteins Springer US; http://www.springer-ny.com 7/1(2015-03-01), 24-30 1867-1306 7:1<24 2015 7 12602 https://doi.org/10.1007/s12602-014-9175-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12602-014-9175-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sadeghi Ali Department of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran aut NATIONALLICENCE 700 1- Shawrang Parvin Nuclear Agriculture Research School, Nuclear Science and Technology Research Institute, AEOI, Karaj, Iran aut NATIONALLICENCE 700 1- Shakorzadeh Shirin Department of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran aut NATIONALLICENCE 773 0- Probiotics and Antimicrobial Proteins Springer US; http://www.springer-ny.com 7/1(2015-03-01), 24-30 1867-1306 7:1<24 2015 7 12602