caa a22 4500 606242503 CHVBK 20210128101319.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s12602-014-9172-4 doi (NATIONALLICENCE)springer-10.1007/s12602-014-9172-4 Morphofunctional Reaction of Bacteria Treated with Antimicrobial Peptides Derived from Farm Animal Platelets [Elektronische Daten] [Alexey Vasilchenko, Veronica Dymova, Olga Kartashova, Maria Sycheva] Classical microbiological approach and atomic force microscopy were used to evaluate the mechanisms of biological activity of antimicrobial peptides (AMPs) derived from platelets of farm animals. It is established that AMPs inhibit both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) microorganisms. Differences revealed in the biological activity of AMP preparations obtained from the organisms of various species can be reduced to quantitative differences. While qualitative changes of bacterial cells were substantially similar, changes in the integrity of cell walls resulted in disintegration of the bacterial outer and/or cytoplasmic membranes. Springer Science+Business Media New York, 2014 Antimicrobial peptides nationallicence Antibiotics nationallicence Atomic force microscopy nationallicence Platelet microbicidal proteins nationallicence Farm animals nationallicence Vasilchenko Alexey Orenburg State University, Pobedy Ave, 13, 460018, Orenburg, Russia aut Dymova Veronica Orenburg State Agrarian University, Chelyuskintsev Str, 18, 460795, Orenburg, Russia aut Kartashova Olga Institute of Cellular and Intracellular Symbiosis, RAS, Pionerskaya Str, 11, 460000, Orenburg, Russia aut Sycheva Maria Institute of Cellular and Intracellular Symbiosis, RAS, Pionerskaya Str, 11, 460000, Orenburg, Russia aut Probiotics and Antimicrobial Proteins Springer US; http://www.springer-ny.com 7/1(2015-03-01), 60-65 1867-1306 7:1<60 2015 7 12602 https://doi.org/10.1007/s12602-014-9172-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12602-014-9172-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vasilchenko Alexey Orenburg State University, Pobedy Ave, 13, 460018, Orenburg, Russia aut NATIONALLICENCE 700 1- Dymova Veronica Orenburg State Agrarian University, Chelyuskintsev Str, 18, 460795, Orenburg, Russia aut NATIONALLICENCE 700 1- Kartashova Olga Institute of Cellular and Intracellular Symbiosis, RAS, Pionerskaya Str, 11, 460000, Orenburg, Russia aut NATIONALLICENCE 700 1- Sycheva Maria Institute of Cellular and Intracellular Symbiosis, RAS, Pionerskaya Str, 11, 460000, Orenburg, Russia aut NATIONALLICENCE 773 0- Probiotics and Antimicrobial Proteins Springer US; http://www.springer-ny.com 7/1(2015-03-01), 60-65 1867-1306 7:1<60 2015 7 12602