caa a22 4500 606242856 CHVBK 20210128101321.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s12551-014-0150-6 doi (NATIONALLICENCE)springer-10.1007/s12551-014-0150-6 Cochran JC Department of Molecular & Cellular Biochemistry, Indiana University, Simon Hall Room 405C, 212 S. Hawthorne Dr., 47405, Bloomington, IN, USA aut Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular Machines [Elektronische Daten] [JC Cochran] Molecular motors are enzymes that convert chemical potential energy into controlled kinetic energy for mechanical work inside cells. Understanding the biophysics of these motors is essential for appreciating life as well as apprehending diseases that arise from motormalfunction. This review focuses on kinesin motor enzymology with special emphasis on the literature that reports the chemistry, structure and physics of several different kinesin superfamily members. International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag Berlin Heidelberg, 2015 Molecular motors nationallicence Kinesin motor enzymology nationallicence Kinesin superfamily nationallicence Chemical models nationallicence Enzymes nationallicence AlFx : Aluminum fluoride nationallicence AMPPCP : Adenosine 5′-(β,γ-methylene)triphosphate nationallicence AMPPNP : Adenosine 5′-(β,γ-imido)triphosphate nationallicence ATP : Adenosine 5′-triphosphate nationallicence ATPγS : Adenosine 5′-(γ-thio)triphosphate nationallicence BeFx : Beryllium fluoride nationallicence E : Kinesin nationallicence FRET : Förster resonance energy transfer nationallicence mant-ATP : 2'-(or-3')-O-(N-Methylanthraniloyl) adenosine 5'-triphosphate nationallicence MDCC-PBP : 7-Diethylamino-3-((((2-maleimidyl)ethyl)amino)carbonyl) coumarin)-labeled phosphate binding protein nationallicence MT : Microtubule nationallicence SDS-PAGE : Sodium dodecyl sulfate polyacrylamide gel electrophoresis nationallicence SO4 - : Sulfate nationallicence VO4 - : Vanadate nationallicence Biophysical Reviews Springer Berlin Heidelberg 7/3(2015-09-01), 269-299 1867-2450 7:3<269 2015 7 12551 https://doi.org/10.1007/s12551-014-0150-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12551-014-0150-6 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Cochran JC Department of Molecular & Cellular Biochemistry, Indiana University, Simon Hall Room 405C, 212 S. Hawthorne Dr., 47405, Bloomington, IN, USA aut NATIONALLICENCE 773 0- Biophysical Reviews Springer Berlin Heidelberg 7/3(2015-09-01), 269-299 1867-2450 7:3<269 2015 7 12551