caa a22 4500 606242880 CHVBK 20210128101321.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s12551-015-0177-3 doi (NATIONALLICENCE)springer-10.1007/s12551-015-0177-3 How to test bioinformatics software? [Elektronische Daten] [Amir Kamali, Eleni Giannoulatou, Tsong Chen, Michael Charleston, Alistair McEwan, Joshua Ho] Bioinformatics is the application of computational, mathematical and statistical techniques to solve problems in biology and medicine. Bioinformatics programs developed for computational simulation and large-scale data analysis are widely used in almost all areas of biophysics. The appropriate choice of algorithms and correct implementation of these algorithms are critical for obtaining reliable computational results. Nonetheless, it is often very difficult to systematically test these programs as it is often hard to verify the correctness of the output, and to effectively generate failure-revealing test cases. Software testing is an important process of verification and validation of scientific software, but very few studies have directly dealt with the issues of bioinformatics software testing. In this work, we review important concepts and state-of-the-art methods in the field of software testing. We also discuss recent reports on adapting and implementing software testing methodologies in the bioinformatics field, with specific examples drawn from systems biology and genomic medicine. International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag Berlin Heidelberg, 2015 Software testing nationallicence Bioinformatics nationallicence Quality assurance nationallicence Automated testing nationallicence Cloud-based testing nationallicence Kamali Amir Victor Chang Cardiac Research Institute, 2010, Darlinghurst, NSW, Australia aut Giannoulatou Eleni Victor Chang Cardiac Research Institute, 2010, Darlinghurst, NSW, Australia aut Chen Tsong Department of Computer Science and Software Engineering, Swinburne University of Technology, Melbourne, VIC, Australia aut Charleston Michael School of Physical Sciences, The University of Tasmania, Hobart, TAS, Australia aut McEwan Alistair School of Electrical and Information Engineering, The University of Sydney, 2006, Sydney, NSW, Australia aut Ho Joshua Victor Chang Cardiac Research Institute, 2010, Darlinghurst, NSW, Australia aut Biophysical Reviews Springer Berlin Heidelberg 7/3(2015-09-01), 343-352 1867-2450 7:3<343 2015 7 12551 https://doi.org/10.1007/s12551-015-0177-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12551-015-0177-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kamali Amir Victor Chang Cardiac Research Institute, 2010, Darlinghurst, NSW, Australia aut NATIONALLICENCE 700 1- Giannoulatou Eleni Victor Chang Cardiac Research Institute, 2010, Darlinghurst, NSW, Australia aut NATIONALLICENCE 700 1- Chen Tsong Department of Computer Science and Software Engineering, Swinburne University of Technology, Melbourne, VIC, Australia aut NATIONALLICENCE 700 1- Charleston Michael School of Physical Sciences, The University of Tasmania, Hobart, TAS, Australia aut NATIONALLICENCE 700 1- McEwan Alistair School of Electrical and Information Engineering, The University of Sydney, 2006, Sydney, NSW, Australia aut NATIONALLICENCE 700 1- Ho Joshua Victor Chang Cardiac Research Institute, 2010, Darlinghurst, NSW, Australia aut NATIONALLICENCE 773 0- Biophysical Reviews Springer Berlin Heidelberg 7/3(2015-09-01), 343-352 1867-2450 7:3<343 2015 7 12551