caa a22 4500 606242902 CHVBK 20210128101321.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12551-015-0183-5 doi (NATIONALLICENCE)springer-10.1007/s12551-015-0183-5 Natural isoquinoline alkaloids: binding aspects to functional proteins, serum albumins, hemoglobin, and lysozyme [Elektronische Daten] [Asma Khan, Gopinatha Suresh Kumar] The putative anticancer alkaloids berberine, palmatine, jatrorrhizine, and sanguinarine are known to bind to nucleic acids. To develop them as potential drugs for therapeutic use, their binding affinity to functional proteins and mode of transport in the circulatory system need to be clearly understood. Towards this, many studies on their binding aspects to proteins have been reported and a considerable amount of data, mostly of biophysical nature, exists in the literature. The importance of these natural isoquinoline alkaloids and the recent literature on their interaction phenomena with functional proteins, serum albumins, hemoglobin, and lysozyme are presented in this review. International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag Berlin Heidelberg, 2015 Isoquinoline alkaloids nationallicence Serum albumins nationallicence Hemoglobin nationallicence Lysozyme nationallicence Interaction nationallicence Khan Asma Biophysical Chemistry Laboratory, Organic and Medicinal Chemistry Division, CSIR—Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, 700 032, Kolkata, India aut Suresh Kumar Gopinatha Biophysical Chemistry Laboratory, Organic and Medicinal Chemistry Division, CSIR—Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, 700 032, Kolkata, India aut Biophysical Reviews Springer Berlin Heidelberg 7/4(2015-12-01), 407-420 1867-2450 7:4<407 2015 7 12551 https://doi.org/10.1007/s12551-015-0183-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12551-015-0183-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khan Asma Biophysical Chemistry Laboratory, Organic and Medicinal Chemistry Division, CSIR—Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, 700 032, Kolkata, India aut NATIONALLICENCE 700 1- Suresh Kumar Gopinatha Biophysical Chemistry Laboratory, Organic and Medicinal Chemistry Division, CSIR—Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, 700 032, Kolkata, India aut NATIONALLICENCE 773 0- Biophysical Reviews Springer Berlin Heidelberg 7/4(2015-12-01), 407-420 1867-2450 7:4<407 2015 7 12551