caa a22 4500 606244093 CHVBK 20210128101328.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12596-014-0229-2 doi (NATIONALLICENCE)springer-10.1007/s12596-014-0229-2 Miniaturized bimodal laser scanning microscopes [Elektronische Daten] [Jiaxin Yu, Fuhong Cai, Sailing He] In this paper, we report a miniaturized laser scanning microscope. Unlike conventional microscopes, the optical fiber used here for the excitation laser and signal's transmission largely improves our microscope's mobility, and thus eliminates the space constraints of the sample stage. This miniaturized microscope can be motorized along XYZ axis and rotated in theta direction. Based on this modified microscope, we take images of test targets and a micrometer, and compare the resolution and signal to background ratio between its confocal and non-descanned detection modules. We also present the imaging results of Hela cells on a tilted sample stage to simulate the imaging of large and irregular samples. Therefore, this miniaturized microscope has the potential to be utilized for in vivo imaging of large animals. The Optical Society of India, 2014 Laser scanning microscope nationallicence Miniaturized nationallicence Bimodal imaging nationallicence Bio-imaging nationallicence Yu Jiaxin Centre for Optical and Electromagnetic Research, Zhejiang Key Laboratory of Sensing Technologies, Zhejiang University, 310058, Hangzhou, China aut Cai Fuhong Centre for Optical and Electromagnetic Research, Zhejiang Key Laboratory of Sensing Technologies, Zhejiang University, 310058, Hangzhou, China aut He Sailing Centre for Optical and Electromagnetic Research, Zhejiang Key Laboratory of Sensing Technologies, Zhejiang University, 310058, Hangzhou, China aut Journal of Optics Springer India 44/4(2015-12-01), 405-408 0972-8821 44:4<405 2015 44 12596 https://doi.org/10.1007/s12596-014-0229-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12596-014-0229-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yu Jiaxin Centre for Optical and Electromagnetic Research, Zhejiang Key Laboratory of Sensing Technologies, Zhejiang University, 310058, Hangzhou, China aut NATIONALLICENCE 700 1- Cai Fuhong Centre for Optical and Electromagnetic Research, Zhejiang Key Laboratory of Sensing Technologies, Zhejiang University, 310058, Hangzhou, China aut NATIONALLICENCE 700 1- He Sailing Centre for Optical and Electromagnetic Research, Zhejiang Key Laboratory of Sensing Technologies, Zhejiang University, 310058, Hangzhou, China aut NATIONALLICENCE 773 0- Journal of Optics Springer India 44/4(2015-12-01), 405-408 0972-8821 44:4<405 2015 44 12596