caa a22 4500 606245936 CHVBK 20210128101337.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s12262-015-1208-9 doi (NATIONALLICENCE)springer-10.1007/s12262-015-1208-9 A Sporadic Small Jejunal GIST Presenting with Acute Lower Gastrointestinal Hemorrhage: A Review of the Literature and Management Guidelines [Elektronische Daten] [Sridar Govindaraj, Brendan Dias, S. Gautham] Gastrointestinal stromal tumors (GISTs) represent the majority of primary nonepithelial neoplasms of the digestive tract, most frequently expressing the KIT protein detected by immunohistochemical staining for the CD117 antigen. Jejunal GISTs account for approximately 10% of GISTs. Patients usually present with abdominal discomfort. Jejunal GISTs may cause symptoms secondary to obstruction or hemorrhage. Pressure necrosis and ulceration of the overlying mucosa may cause gastrointestinal bleeding, and patients who experience significant blood loss may suffer from malaise and fatigue. Literature has classified small-bowel GISTs on the basis of size, and various established guidelines have advised conservative management of small jejunal GISTs (<2cm). We here report the clinical, macroscopic, and immunohistological features of a small jejunal GIST presenting with acute lower gastrointestinal hemorrhage in a 50-year-old postmenopausal woman necessitating an emergency laparotomy to control the bleed. The management of very small (<2cm) small-bowel GISTs is controversial. While guidelines are primarily based on the risk of malignancy in GISTs, no guideline predicting the risk of complications in small-bowel GISTs exists. Hence, these tumors should be removed even if incidentally detected. Association of Surgeons of India, 2015 Jejunal GIST nationallicence GIST nationallicence Lower GI bleed nationallicence Govindaraj Sridar Department of General Surgery, St. John's Medical College Hospital, 560034, Bangalore, Karnataka, India aut Dias Brendan Department of General Surgery, St. John's Medical College Hospital, 560034, Bangalore, Karnataka, India aut Gautham S. Department of General Surgery, St. John's Medical College Hospital, 560034, Bangalore, Karnataka, India aut Indian Journal of Surgery Springer India 77(2015-04-01), 143-146 0972-2068 77<143 2015 77 12262 https://doi.org/10.1007/s12262-015-1208-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-015-1208-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Govindaraj Sridar Department of General Surgery, St. John's Medical College Hospital, 560034, Bangalore, Karnataka, India aut NATIONALLICENCE 700 1- Dias Brendan Department of General Surgery, St. John's Medical College Hospital, 560034, Bangalore, Karnataka, India aut NATIONALLICENCE 700 1- Gautham S. Department of General Surgery, St. John's Medical College Hospital, 560034, Bangalore, Karnataka, India aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-04-01), 143-146 0972-2068 77<143 2015 77 12262