caa a22 4500 606246134 CHVBK 20210128101338.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s12262-014-1164-9 doi (NATIONALLICENCE)springer-10.1007/s12262-014-1164-9 Invasive Gastric Mucormycosis—a Case Report [Elektronische Daten] [Rugved Kulkarni, Sanjiv Thakur] Mucormycosis is an opportunistic fungal infection that is associated with high mortality in immunocompromised individuals. While rhinocerebral and pulmonary forms are most common, primary gastrointestinal mucormycosis is very uncommon. The stomach is the most commonly affected organ followed by the colon and ileum in alimentary zygomycosis. We report a rare case of invasive gastric mucormycosis in a 50-year-old diabetic gentleman with a history of chronic alcoholism presenting with complaints of pain and distension of the abdomen for 6days associated with fever, nausea, vomiting and anorexia. At presentation, he was hemodynamically unstable, febrile with uncontrolled blood sugar level and had negative HIV serology. There was generalized guarding, rigidity and distension of the abdomen and investigations confirmed perforative peritonitis. Upon exploration, there was solitary large 4 × 4cm size perforated ulcer in the gastric body with greenish, greyish sloughed out mucosa within. Wedge resection of the ulcer with primary closure was performed. Histopathology revealed aseptate, broad, obtuse angled fungal hyphae, and invasive mucormycosis was confirmed by special stains like Periodic acid-Schiff (PAS) and Gomori′s methenamine silver (GMS). Very few cases of invasive gastric mucormycosis associated with uncontrolled diabetes and alcoholism have been reported in the literature. Delayed presentation of the patient along with rapid progression to fungal septicaemia resulted in the case fatality despite early surgical intervention and critical care management. Association of Surgeons of India, 2014 Invasive gastric mucormycosis nationallicence Perforative peritonitis nationallicence Diabetes nationallicence Alcoholism nationallicence Kulkarni Rugved Department of General Surgery, Byramjee Jeejeebhoy Medical College, 411001, Pune, Maharashtra, India aut Thakur Sanjiv Department of General Surgery, Byramjee Jeejeebhoy Medical College, 411001, Pune, Maharashtra, India aut Indian Journal of Surgery Springer India 77(2015-04-01), 87-89 0972-2068 77<87 2015 77 12262 https://doi.org/10.1007/s12262-014-1164-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-014-1164-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kulkarni Rugved Department of General Surgery, Byramjee Jeejeebhoy Medical College, 411001, Pune, Maharashtra, India aut NATIONALLICENCE 700 1- Thakur Sanjiv Department of General Surgery, Byramjee Jeejeebhoy Medical College, 411001, Pune, Maharashtra, India aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-04-01), 87-89 0972-2068 77<87 2015 77 12262