caa a22 4500 60624624X CHVBK 20210128101339.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s12262-014-1178-3 doi (NATIONALLICENCE)springer-10.1007/s12262-014-1178-3 Peutz-Jeghers Syndrome with Synchronous Adenocarcinoma Arising from Ileal Polyps [Elektronische Daten] [Mohit Sharma, Rachhpal Singh, Anumeet Grover] Peutz-Jeghers syndrome is a rare inherited autosomal disease characterized by mucocutaneous pigmentation and multiple polyps in the gastrointestinal tract. The clinical picture is characterized by repeated episodes of polyp-induced intestinal obstruction, abdominal pain, and bleeding per rectum. Predisposition to both gastrointestinal and nongastrointestinal malignancies is increased in a patient with Peutz-Jeghers syndrome. This is a case report of a 29-year-old male with Peutz-Jeghers syndrome who presented with a complaint of recurrent abdominal pain. CT scan revealed a single obstructing ileal polyp. However, preoperatively, another large ileal polyp with multiple small jejunal polyps was seen. Histopathology of both ileal polyps was identified as a mucinous adenocarcinoma infiltrating up to the serosa. The follow-up endoscopies showed small multiple polyps in the stomach, duodenum, and colon. Histopathology of all endoscopically removed polyps was consistent with the diagnosis of hamartomatous polyps. Very few cases of intestinal intussusception combined with synchronous malignant small intestine polyps have been reported until to date. Association of Surgeons of India, 2014 Peutz-Jeghers syndrome nationallicence Synchronous ileal cancer nationallicence Hamartomatous polyps nationallicence Polypectomy nationallicence Sharma Mohit Department of Surgery, Sri Guru Ramdass Institute of Medical Sciences and Research, 1843 New State Bank Colony, Race Course Road, Vallah, 143001, Amritsar, India aut Singh Rachhpal Department of Surgery, Sri Guru Ramdass Institute of Medical Sciences and Research, Vallah, Amritsar, India aut Grover Anumeet Department of Medicine, Sri Guru Ramdass Institute of Medical Sciences and Research, Vallah, Amritsar, India aut Indian Journal of Surgery Springer India 77(2015-04-01), 100-102 0972-2068 77<100 2015 77 12262 https://doi.org/10.1007/s12262-014-1178-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-014-1178-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sharma Mohit Department of Surgery, Sri Guru Ramdass Institute of Medical Sciences and Research, 1843 New State Bank Colony, Race Course Road, Vallah, 143001, Amritsar, India aut NATIONALLICENCE 700 1- Singh Rachhpal Department of Surgery, Sri Guru Ramdass Institute of Medical Sciences and Research, Vallah, Amritsar, India aut NATIONALLICENCE 700 1- Grover Anumeet Department of Medicine, Sri Guru Ramdass Institute of Medical Sciences and Research, Vallah, Amritsar, India aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-04-01), 100-102 0972-2068 77<100 2015 77 12262