caa a22 4500 606246649 CHVBK 20210128101341.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12262-012-0771-6 doi (NATIONALLICENCE)springer-10.1007/s12262-012-0771-6 Surgical Treatment of Extrapulmonary Oligometastatic Non-small Cell Lung Cancer [Elektronische Daten] [Till Plönes, Thomas Osei-Agyemang, Alexander Krohn, Bernward Passlick] The prognosis of metastatic non-small cell lung cancer (NSCLC) is poor, and platinum-based chemotherapy improves the median survival for only a few months. A subgroup of patients with oligometastatic disease may benefit from surgical resection, but only very limited data are available to date. We conducted a retrospective review of all patients with synchronous extrapulmonary oligometastatic NSCLC undergoing surgical resection in our department. Data regarding medical history, histology, number of metastases, and survival status were extracted from the medical database of the University Medical Center, Freiburg. Fifty-six patients underwent surgical resection for oligometastatic lung cancer. Five patients were lost during follow-up and therefore censored. One patient died perioperatively due to acute respiratory distress syndrome. The remaining 50 patients had an overall median survival time of 14.6months. Analyzing the influence of metastatic site, we found a median overall survival of 23.4months for patients with soft tissue metastasis, 16.7months for patients with brain metastasis, 9.5months for patients with adrenal gland involvement, and only 4.3months for patients with bone metastasis (p < 0.005). Upon multivariate analysis, bone metastasis was the only significant parameter influencing median overall survival (p < 0.004). Based on our data, we conclude that an aggressive surgical approach for oligometastatic NSCLC can be performed with acceptable mortality and morbidity. In this rare constellation, surgical therapy may be an option in selected cases. Association of Surgeons of India, 2012 NSCLC nationallicence Single metastasis nationallicence Stage nationallicence Skip metastasis nationallicence Plönes Till Department of Thoracic Surgery, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut Osei-Agyemang Thomas Department of Thoracic Surgery, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut Krohn Alexander Department of Oncology and Haematology, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut Passlick Bernward Department of Thoracic Surgery, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut Indian Journal of Surgery Springer India 77(2015-12-01), 216-220 0972-2068 77<216 2015 77 12262 https://doi.org/10.1007/s12262-012-0771-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-012-0771-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Plönes Till Department of Thoracic Surgery, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut NATIONALLICENCE 700 1- Osei-Agyemang Thomas Department of Thoracic Surgery, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut NATIONALLICENCE 700 1- Krohn Alexander Department of Oncology and Haematology, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut NATIONALLICENCE 700 1- Passlick Bernward Department of Thoracic Surgery, University Medical Center Freiburg, Hugstetterstrasse 55, 79106, Freiburg im Breisgau, Germany aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-12-01), 216-220 0972-2068 77<216 2015 77 12262