caa a22 4500 606246797 CHVBK 20210128101342.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12262-013-0853-0 doi (NATIONALLICENCE)springer-10.1007/s12262-013-0853-0 Laparoscopic Peptic Ulcer Perforation Closure: the Preferred Choice [Elektronische Daten] [Franal Shah, Sudhir Mehta, Mona Gandhi, Saraj,] Peptic ulcer perforation is a common life-threatening emergency needing immediate intervention. Laparoscopic closure of perforation is now widely practiced over conventional open closure. This study aimed to compare laparoscopic peptic ulcer perforation closure with conventional open closure in terms of operative time, postoperative analgesia, complications, hospital stay, and return to routine activities. This unicentric, nonblinded, prospective, randomized study was carried out in 50 patients with peptic ulcer perforation who were randomly allocated to undergo either laparoscopic closure or open closure surgery with 25 patients in each group. The mean operative time (60 vs 90min) was less in the laparoscopic group (p < 0.05). Postoperative analgesia requirements (1 vs 6days) were also less in laparoscopic patients (p < 0.05). Complications (nil vs 6; p < 0.05) and hospital stay (3 vs 8days) were less in laparoscopic patients (p < 0.05). Patients return to normal activities (5 vs 10days; p < 0.05) earlier in laparoscopic perforation closure than in open closure. Our study has shown better outcomes and lesser morbidities with laparoscopic approach in terms of shorter operative time, shorter hospital stay, less analgesic requirements, and less wound infections. Patients also return to routine activities earlier with the laparoscopic approach. It is a safe alternative to open surgery and should be a preferred choice when there are no contraindications to laparoscopy. Association of Surgeons of India, 2013 Peptic ulcer perforation nationallicence Laparoscopic closure nationallicence Open closure nationallicence Shah Franal Department of Surgery, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut Mehta Sudhir Department of Surgery, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut Gandhi Mona Department of Obstetric and Gynecology, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut Saraj, Department of Surgery, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut Indian Journal of Surgery Springer India 77(2015-12-01), 403-406 0972-2068 77<403 2015 77 12262 https://doi.org/10.1007/s12262-013-0853-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-013-0853-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shah Franal Department of Surgery, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut NATIONALLICENCE 700 1- Mehta Sudhir Department of Surgery, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut NATIONALLICENCE 700 1- Gandhi Mona Department of Obstetric and Gynecology, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut NATIONALLICENCE 700 1- Saraj Department of Surgery, M.P. Shah Medical College, P.N. Marg, Jamnagar, India aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-12-01), 403-406 0972-2068 77<403 2015 77 12262