caa a22 4500 606246894 CHVBK 20210128101342.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12262-013-0904-6 doi (NATIONALLICENCE)springer-10.1007/s12262-013-0904-6 Histopathological Comparison of Mosquito Net with Polypropylene Mesh for Hernia Repair: An Experimental Study in Rats [Elektronische Daten] [Mukesh Sharma, Deepti Sharma, Shiv Chandrakar, Dhananjaya Sharma] Use of mosquito net, in place of polypropylene mesh, had been reported for tension-free hernia repair, as a better cost-effective option. This experimental histopathological study was performed in rats to find out the tissue response and the foreign body reaction and its comparison between commercial polypropylene mesh and the sterilized mosquito net. This experimental study was conducted in the Department of Surgery, Government NSCB, Medical College, Jabalpur (Madhya Pradesh), India. It was carried out in 40 albino rats. A 1.5 × 0.5-cm hernial defect was created by excising full-thickness abdominal wall muscle. All rats underwent on-lay mesh repair of hernial defect (polypropylene mesh, n = 20; mosquito net, n = 20). Half of rats in each group were sacrificed on day 14, and the other half, on day 90. Sections of containing mesh were examined histopathologically for inflammatory infiltrate, giant cells, and collagen deposition. Mosquito net group showed significantly greater number of giant cells and inflammatory cells at 14 and 90days (p < 0.0001, p < 0.001, p < 0.05, and p < 0.001, respectively), as compared to polypropylene group. Grades of collagen fiber deposition were almost equal in both groups, both at 14 and 90days (p > 0.05 and p > 0.05, respectively). Results of mosquito net are comparable to conventional polypropylene mesh. In a setup, where cost-effectiveness is of primary importance, use of mosquito net for tension-free hernia repair can be an acceptable alternative as proven histologically, to commercially available polypropylene mesh. Association of Surgeons of India, 2013 Hernia nationallicence Histological study nationallicence Mosquito net nationallicence Sharma Mukesh Department of Surgery, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut Sharma Deepti Department of Surgery, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut Chandrakar Shiv Department of Pathology, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut Sharma Dhananjaya Department of Surgery, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut Indian Journal of Surgery Springer India 77(2015-12-01), 511-514 0972-2068 77<511 2015 77 12262 https://doi.org/10.1007/s12262-013-0904-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-013-0904-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sharma Mukesh Department of Surgery, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut NATIONALLICENCE 700 1- Sharma Deepti Department of Surgery, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut NATIONALLICENCE 700 1- Chandrakar Shiv Department of Pathology, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut NATIONALLICENCE 700 1- Sharma Dhananjaya Department of Surgery, Government NSCB Medical College, 482 003, Jabalpur, Madhya Pradesh, India aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-12-01), 511-514 0972-2068 77<511 2015 77 12262