caa a22 4500 606246975 CHVBK 20210128105231.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12262-013-0961-x doi (NATIONALLICENCE)springer-10.1007/s12262-013-0961-x Post-mortem Reperfusion of a Pig: a First Step to a New Surgical Training Model? [Elektronische Daten] [Wouter Willaert, Filip De Somer, Silke Grabherr, Katharina D'Herde, Piet Pattyn] The purpose of this experimental study was to establish a short-term post-mortem circulation in a pig model using liquid paraffin. This study also investigated the quality of vascular perfusion in the peripheral tissues. This is the first step in the development of a new revascularized human surgical training model. This first experience was performed on the hind leg of a pig. Initial cannulation of the external iliac artery and vein was followed by connection of the arterial inflow to a heart-lung machine and using the venous outflow to flush post-mortem clots and blood. Subsequently, after connecting the venous outflow to the heart-lung machine, circulation was initiated. Circulation was established during 27min, during which the flow was constantly 130mL/min. A steady increase in inlet pressure was observed during the experiment, which finally reached a minimum value of 124mmHg. Perfusion was interrupted early due to an uncontrollable fluid leak. Afterwards, the distal hind leg was incised showing an equal distribution of paraffin. A short-term revascularization was successfully re-established under excellent conditions. Although the results are promising, further experiments are necessary to eventually perform a wide range of surgical procedures on revascularized human cadavers. Association of Surgeons of India, 2013 Heart-lung machine nationallicence Paraffin nationallicence Perfusion nationallicence Swine nationallicence Post-mortem nationallicence Willaert Wouter Department of Gastrointestinal Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut De Somer Filip Department of Cardiac Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut Grabherr Silke University Centre of Legal Medicine Lausanne-Geneva, University of Lausanne, Rue du Bugnon 21, CH-1011, Lausanne, Switzerland aut D'Herde Katharina Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut Pattyn Piet Department of Gastrointestinal Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut Indian Journal of Surgery Springer India 77(2015-12-01), 712-715 0972-2068 77<712 2015 77 12262 https://doi.org/10.1007/s12262-013-0961-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-013-0961-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Willaert Wouter Department of Gastrointestinal Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut NATIONALLICENCE 700 1- De Somer Filip Department of Cardiac Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut NATIONALLICENCE 700 1- Grabherr Silke University Centre of Legal Medicine Lausanne-Geneva, University of Lausanne, Rue du Bugnon 21, CH-1011, Lausanne, Switzerland aut NATIONALLICENCE 700 1- D'Herde Katharina Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut NATIONALLICENCE 700 1- Pattyn Piet Department of Gastrointestinal Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-12-01), 712-715 0972-2068 77<712 2015 77 12262 SWISSBIB 365607487