caa a22 4500 606249109 CHVBK 20210128101354.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s12262-014-1112-8 doi (NATIONALLICENCE)springer-10.1007/s12262-014-1112-8 Procalcitonin Strip Test as an Independent Predictor in Acute Pancreatitis [Elektronische Daten] [Brendan Dias, Anthony Rozario, Santosh Olakkengil, Anirudh V.] Plasma procalcitonin (PCT) is a highly specific marker for the diagnosis of bacterial infection and sepsis. Studies have demonstrated its role in the setting of sepsis and acute pancreatitis. This study aims to analyze and compare the prognostic efficacy of plasma procalcitonin strip test in acute pancreatitis. A prospective study was conducted in the department of general surgery from June 2012 to June 2013. Plasma procalcitonin was estimated by the semiquantitative strip test. The study included a total of 50 patients diagnosed to have acute pancreatitis. Data was collected and statistically analyzed using SPSS version 17. Thirty-nine out of the 50 patients (78%) were males with a mean age of 46.8years (range, 25-78years) and 25 patients (50%) had ethanol-induced pancreatitis, while 13 patients (26%) had gall stone pancreatitis. Plasma PCT values were found to correlate better than CRP levels and total leukocyte count with the total duration of hospitalization, ITU, and ICU stay, as well as with the progression to severe acute pancreatitis. A cut off for plasma PCT of >2ng/mL was found to be 100% sensitive and 100% specific and a cut off for CRP of >19mg/dL was 70% sensitive and 65% specific for predicting the progression to severe acute pancreatitis. Plasma PCT also correlated well with antibiotic requirement. A cut off value of >0.5ng/mL for plasma PCT was 100% sensitive and 80% specific and a cut off value of >18mg/dL for CRP was 86% sensitive and 63% specific for predicting antibiotic requirement. Plasma procalcitonin is an early and reliable prognostic indicator in acute pancreatitis. The procalcitonin strip test is a rapid test which is useful in analyzing prognosis in patients with acute pancreatitis. Association of Surgeons of India, 2014 Procalcitonin nationallicence Acute abdomen nationallicence Acute pancreatitis nationallicence C-reactive protein nationallicence CRP nationallicence PCT nationallicence Procalcitonin strip test nationallicence Dias Brendan Department of General Surgery, St. John's Medical College, St. John's Mens Hostel, Sarjapura road, Koramangala, Bangalore, India aut Rozario Anthony Department of General Surgery, St. John's Medical College Hospital, Sarjapura road, Koramangala, Bangalore, Karnataka, India aut Olakkengil Santosh Department of General Surgery, St. John's Medical College Hospital, Sarjapura road, Koramangala, Bangalore, Karnataka, India aut V. Anirudh Department of General Surgery, St. John's Medical College Hospital, Sarjapura road, Koramangala, Bangalore, Karnataka, India aut Indian Journal of Surgery Springer India 77(2015-12-01), 1012-1017 0972-2068 77<1012 2015 77 12262 https://doi.org/10.1007/s12262-014-1112-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s12262-014-1112-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dias Brendan Department of General Surgery, St. John's Medical College, St. John's Mens Hostel, Sarjapura road, Koramangala, Bangalore, India aut NATIONALLICENCE 700 1- Rozario Anthony Department of General Surgery, St. John's Medical College Hospital, Sarjapura road, Koramangala, Bangalore, Karnataka, India aut NATIONALLICENCE 700 1- Olakkengil Santosh Department of General Surgery, St. John's Medical College Hospital, Sarjapura road, Koramangala, Bangalore, Karnataka, India aut NATIONALLICENCE 700 1- V Anirudh Department of General Surgery, St. John's Medical College Hospital, Sarjapura road, Koramangala, Bangalore, Karnataka, India aut NATIONALLICENCE 773 0- Indian Journal of Surgery Springer India 77(2015-12-01), 1012-1017 0972-2068 77<1012 2015 77 12262