Additive effect of elcatonin to risedronate for chronic back pain and quality of life in postmenopausal women with osteoporosis: a randomized controlled trial
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 605463336 | ||
| 003 | CHVBK | ||
| 005 | 20210128100252.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150701xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00774-014-0603-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00774-014-0603-9 | ||
| 245 | 0 | 0 | |a Additive effect of elcatonin to risedronate for chronic back pain and quality of life in postmenopausal women with osteoporosis: a randomized controlled trial |h [Elektronische Daten] |c [Michio Hongo, Naohisa Miyakoshi, Yuji Kasukawa, Yoshinori Ishikawa, Yoichi Shimada] |
| 520 | 3 | |a Calcitonin has been reported to reduce acute and chronic back pain in osteoporotic patients. The additive effect of calcitonin with a bisphosphonate on chronic back pain remains unclear. The purpose of this study was to evaluate the effect of combining elcatonin (eel calcitonin) with risedronate for patients with chronic back pain. Forty-five postmenopausal women diagnosed as having osteoporosis with chronic back pain persisting for more than 3months, after excluding women with fresh vertebral fractures within the last 6months, were randomly allocated to a risedronate group (risedronate alone, n=22) and a combined group (risedronate and elcatonin, n=23). The study period was 6months. Pain was evaluated with a visual analogue scale (VAS) and the Roland-Morris questionnaire (RDQ). Back extensor strength, bone mineral density, and quality of life on the SF-36 and the Japanese osteoporosis quality of life score were also evaluated. Significant improvements were found in the combined group for VAS at final follow-up compared with baseline and 3months, mental health status on the SF-36, and JOQOL domains for back pain and general health. The JOQOL domain for back pain improved significantly, but no change was found in the VAS or other domains in the risedronate group. Bone mineral density increased significantly in the two groups, but no significant difference was found between the groups. Back extensor strength did not change in both groups. In conclusion, the use of elcatonin in addition to risedronate for more than 3months reduced chronic back pain. The additional therapy of risedronate with elcatonin may be a useful and practical choice for the treatment of osteoporosis with chronic back pain persisting more than 3months. | |
| 540 | |a The Japanese Society for Bone and Mineral Research and Springer Japan, 2014 | ||
| 690 | 7 | |a Elcatonin |2 nationallicence | |
| 690 | 7 | |a Risedronate |2 nationallicence | |
| 690 | 7 | |a Chronic back pain |2 nationallicence | |
| 690 | 7 | |a Osteoporosis |2 nationallicence | |
| 700 | 1 | |a Hongo |D Michio |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | |
| 700 | 1 | |a Miyakoshi |D Naohisa |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | |
| 700 | 1 | |a Kasukawa |D Yuji |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | |
| 700 | 1 | |a Ishikawa |D Yoshinori |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | |
| 700 | 1 | |a Shimada |D Yoichi |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | |
| 773 | 0 | |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/4(2015-07-01), 432-439 |x 0914-8779 |q 33:4<432 |1 2015 |2 33 |o 774 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00774-014-0603-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00774-014-0603-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Hongo |D Michio |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Miyakoshi |D Naohisa |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kasukawa |D Yuji |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ishikawa |D Yoshinori |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shimada |D Yoichi |u Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, 010-8543, Akita, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/4(2015-07-01), 432-439 |x 0914-8779 |q 33:4<432 |1 2015 |2 33 |o 774 | ||