Cellular aggregate capture by fluidic manipulation device highly compatible with micro-well-plates

Verfasser / Beitragende:
[Satoshi Konishi, Yumi Teramachi, Shuhei Shimomura, Wataru Tonomura, Shuhei Tajima, Yasuhiko Tabata]
Ort, Verlag, Jahr:
2015
Enthalten in:
Biomedical Microdevices, 17/3(2015-06-01), 1-6
Format:
Artikel (online)
ID: 605479771
LEADER caa a22 4500
001 605479771
003 CHVBK
005 20210128100411.0
007 cr unu---uuuuu
008 210128e20150601xx s 000 0 eng
024 7 0 |a 10.1007/s10544-015-9953-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10544-015-9953-x 
245 0 0 |a Cellular aggregate capture by fluidic manipulation device highly compatible with micro-well-plates  |h [Elektronische Daten]  |c [Satoshi Konishi, Yumi Teramachi, Shuhei Shimomura, Wataru Tonomura, Shuhei Tajima, Yasuhiko Tabata] 
520 3 |a This paper proposes a capture device to manipulate and transport a cellular aggregate in a micro-well. A cellular aggregate (a few hundreds μm in diameter) is currently manipulated by a pipette. The manual manipulation by a pipette has problems; low reliability, low throughput, and difficulty in confirmation of task completion. We took into account of compatibility with existing methods such as a micro-well-plate and designed for the capture device of a cellular aggregate in a micro-well. A newly developed capture device flows and carries a cellular aggregate from a bottom of a well to a trap of the capture device. We designed a curved surface at the bottom of the capture device to form a space to act as a channel between the inner wall of the micro-well. This paper presents concept, design, fabrication, and of the proposed cellular aggregate capture, followed by successful experimental results. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Cellular aggregate  |2 nationallicence 
690 7 |a uTAS  |2 nationallicence 
690 7 |a Capture  |2 nationallicence 
690 7 |a Fluidic manipulation  |2 nationallicence 
690 7 |a Micro-well-plate  |2 nationallicence 
700 1 |a Konishi  |D Satoshi  |u Department of Mechanical Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
700 1 |a Teramachi  |D Yumi  |u Graduate School of Science and Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
700 1 |a Shimomura  |D Shuhei  |u Graduate School of Science and Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
700 1 |a Tonomura  |D Wataru  |u Department of Mechanical Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
700 1 |a Tajima  |D Shuhei  |u Institute for Frontier Medical Sciences, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, 606-8507, Kyoto, Japan  |4 aut 
700 1 |a Tabata  |D Yasuhiko  |u Institute for Frontier Medical Sciences, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, 606-8507, Kyoto, Japan  |4 aut 
773 0 |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/3(2015-06-01), 1-6  |x 1387-2176  |q 17:3<1  |1 2015  |2 17  |o 10544 
856 4 0 |u https://doi.org/10.1007/s10544-015-9953-x  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10544-015-9953-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Konishi  |D Satoshi  |u Department of Mechanical Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Teramachi  |D Yumi  |u Graduate School of Science and Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shimomura  |D Shuhei  |u Graduate School of Science and Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tonomura  |D Wataru  |u Department of Mechanical Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, 525-8577, Kusatsu, Shiga, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tajima  |D Shuhei  |u Institute for Frontier Medical Sciences, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, 606-8507, Kyoto, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tabata  |D Yasuhiko  |u Institute for Frontier Medical Sciences, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, 606-8507, Kyoto, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/3(2015-06-01), 1-6  |x 1387-2176  |q 17:3<1  |1 2015  |2 17  |o 10544