Facile microfluidic channels for acoustophoresis on a budget

Verfasser / Beitragende:
[Champika Samarasekera, John Yeow]
Ort, Verlag, Jahr:
2015
Enthalten in:
Biomedical Microdevices, 17/5(2015-10-01), 1-8
Format:
Artikel (online)
ID: 605480028
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024 7 0 |a 10.1007/s10544-015-0006-2  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10544-015-0006-2 
245 0 0 |a Facile microfluidic channels for acoustophoresis on a budget  |h [Elektronische Daten]  |c [Champika Samarasekera, John Yeow] 
520 3 |a Acoustophoresis is a powerful yet gentle technique for manipulating cells and particles that has quickly earned a place in the lab-on-a-chip toolkit. However, traditional construction techniques for acoustophoretic resonators have typically required prohibitively expensive and laborious processing methods. Here, we propose a highly cost-effective and cleanroom-free construction technique for transversal acoustophoretic resonators. Channels with two different widths of 750 and 300μm were constructed using a simple glass and polyimide sandwiching technique. Half and full wavelength resonators were then established using 1 and 5MHz ultrasound respectively and polystyrene beads were successfully manipulated in both types of resonators. This construction technique was then utilized to demonstrate a bifurcation and trifurcation microchannel with 600μm widths and 2.5MHz ultrasound. Our approach addresses some of the key drawbacks of acoustophoretic devices by drastically simplifying the fabrication and prototyping of transversal resonators and will assist in expanding this technology from laboratory benches and into the broader market. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Acoustophoresis  |2 nationallicence 
690 7 |a Microfluidics  |2 nationallicence 
690 7 |a Rapid prototyping  |2 nationallicence 
690 7 |a Bifurcation  |2 nationallicence 
690 7 |a Trifurcation  |2 nationallicence 
700 1 |a Samarasekera  |D Champika  |u Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, Ontario, Canada  |4 aut 
700 1 |a Yeow  |D John  |u Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, Ontario, Canada  |4 aut 
773 0 |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/5(2015-10-01), 1-8  |x 1387-2176  |q 17:5<1  |1 2015  |2 17  |o 10544 
856 4 0 |u https://doi.org/10.1007/s10544-015-0006-2  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10544-015-0006-2  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Samarasekera  |D Champika  |u Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, Ontario, Canada  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yeow  |D John  |u Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, Ontario, Canada  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/5(2015-10-01), 1-8  |x 1387-2176  |q 17:5<1  |1 2015  |2 17  |o 10544