Piezo-actuated parallel mechanism for biological cell release at high speed

Verfasser / Beitragende:
[Ebubekir Avci, Takayuki Hattori, Kazuto Kamiyama, Masaru Kojima, Mitsuhiro Horade, Yasushi Mae, Tatsuo Arai]
Ort, Verlag, Jahr:
2015
Enthalten in:
Biomedical Microdevices, 17/5(2015-10-01), 1-10
Format:
Artikel (online)
ID: 605480125
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024 7 0 |a 10.1007/s10544-015-0001-7  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10544-015-0001-7 
245 0 0 |a Piezo-actuated parallel mechanism for biological cell release at high speed  |h [Elektronische Daten]  |c [Ebubekir Avci, Takayuki Hattori, Kazuto Kamiyama, Masaru Kojima, Mitsuhiro Horade, Yasushi Mae, Tatsuo Arai] 
520 3 |a In this paper, a dynamic releasing approach is proposed for high-speed biological cell manipulation. A compact parallel mechanism for grasping and releasing microobjects is used to generate controllable vibration to overcome the strong adhesion forces between the end effector and the manipulated object. To reach the required acceleration of the end effector, which is necessary for the detachment of the target object by overcoming adhesion forces, vibration in the end effector is generated by applying sinusoidal voltage to the PZT actuator of the parallel mechanism. For the necessary acceleration, we focus on the possible range of the frequency of the PZT-actuator-induced vibration, while minimizing the amplitude of the vibration (14 nm) to achieve precise positioning. The effect of the air and liquid environments on the required vibration frequency for successful release is investigated. For the first time, release results of microbeads and biological cells are compared. Release of the biological cells with 100 % success rate suggests that the proposed active release method is an appropriate solution for adhered biological cells during the release task. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Cell handling  |2 nationallicence 
690 7 |a Micro-scale release  |2 nationallicence 
690 7 |a Controlled vibration  |2 nationallicence 
690 7 |a Micro-manipulation  |2 nationallicence 
690 7 |a Piezo actuator  |2 nationallicence 
700 1 |a Avci  |D Ebubekir  |u The Hamlyn Centre for Robotic Surgery, Imperial College London, SW7 2AZ, London, UK  |4 aut 
700 1 |a Hattori  |D Takayuki  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
700 1 |a Kamiyama  |D Kazuto  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
700 1 |a Kojima  |D Masaru  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
700 1 |a Horade  |D Mitsuhiro  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
700 1 |a Mae  |D Yasushi  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
700 1 |a Arai  |D Tatsuo  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
773 0 |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/5(2015-10-01), 1-10  |x 1387-2176  |q 17:5<1  |1 2015  |2 17  |o 10544 
856 4 0 |u https://doi.org/10.1007/s10544-015-0001-7  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10544-015-0001-7  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Avci  |D Ebubekir  |u The Hamlyn Centre for Robotic Surgery, Imperial College London, SW7 2AZ, London, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hattori  |D Takayuki  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kamiyama  |D Kazuto  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kojima  |D Masaru  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Horade  |D Mitsuhiro  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mae  |D Yasushi  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Arai  |D Tatsuo  |u Department of Systems Innovation, Osaka University, 1-3 Machikaneyama, 560-8531, Toyonaka, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/5(2015-10-01), 1-10  |x 1387-2176  |q 17:5<1  |1 2015  |2 17  |o 10544