Comparison of therapeutic results from radiofrequency ablation and stereotactic body radiotherapy in solitary lung tumors measuring 5cm or smaller
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| 024 | 7 | 0 | |a 10.1007/s10147-014-0741-z |2 doi |
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| 245 | 0 | 0 | |a Comparison of therapeutic results from radiofrequency ablation and stereotactic body radiotherapy in solitary lung tumors measuring 5cm or smaller |h [Elektronische Daten] |c [Satoru Ochiai, Koichiro Yamakado, Hiroshi Kodama, Yoshihito Nomoto, Noriko Ii, Haruyuki Takaki, Hajime Sakuma] |
| 520 | 3 | |a Backgrounds: This retrospective study was conducted to compare the clinical outcomes of radiofrequency ablation (RFA) with those of stereotactic body radiotherapy (SBRT) in patients with lung tumors. Methods: Local tumor progression, adverse events, and overall survival were compared in patients who underwent either RFA or SBRT for a single lung tumor measuring 5cm or smaller. This study was approved by the institutional review boards of two institutions. Informed consent was waived. Results: During September 2009 to June 2012, 48 patients [30 males and 18 females, with a mean age±standard deviation (SD) of 75.0±7.5years] underwent RFA at one institution and 47 patients (21 males and 26 females, with a mean age±SD of 77.0±7.5years) underwent SBRT in another. The mean maximum tumor diameter±SD was 2.0±0.8cm (range 0.6−3.9cm) in the RFA group, and 2.1±0.9cm (range 0.8-4.7cm, p=0.539) in the SBRT group. The RFA and SBRT groups showed similar 3-year local tumor progression [9.6%, 95% confidence interval (CI) 3.6-23.9% vs. 7.0%, 95% CI 0.2-20.2%, p=0.746] and overall survival rates (86.4%, 95% CI 69.2-94.3% vs. 79.6%, 95% CI 60.6-90.1%, p=0.738). No factor significantly affected local tumor progression. A maximum tumor size of 2cm was identified as a prognostic factor in both univariate and multivariate analyses. No death was related to treatment procedures. Major complication rates (Grade 3 adverse events) of the RFA (10.4%, 5/48) and SBRT (8.5%, 4/47, p>0.999) groups were similar. Conclusion: For lung tumor patients, lung RFA provided local tumor control and survival that were similar to those achieved using SBRT, with equal safety. | |
| 540 | |a Japan Society of Clinical Oncology, 2014 | ||
| 690 | 7 | |a Lung tumors |2 nationallicence | |
| 690 | 7 | |a Radiofrequency ablation |2 nationallicence | |
| 690 | 7 | |a Stereotactic body radiotherapy |2 nationallicence | |
| 690 | 7 | |a Prognosis |2 nationallicence | |
| 690 | 7 | |a Complication |2 nationallicence | |
| 700 | 1 | |a Ochiai |D Satoru |u Department of Radiation Oncology, Matsusaka Central Hospital, 102 Kobou Kawaimachi, 515-8566, Matsusaka, Mie, Japan |4 aut | |
| 700 | 1 | |a Yamakado |D Koichiro |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | |
| 700 | 1 | |a Kodama |D Hiroshi |u Department of Radiology, Suzuka Central Hospital, 1275-53 Yamanohana Yasuduka-cho, 513-0818, Suzuka, Mie, Japan |4 aut | |
| 700 | 1 | |a Nomoto |D Yoshihito |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | |
| 700 | 1 | |a Ii |D Noriko |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | |
| 700 | 1 | |a Takaki |D Haruyuki |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | |
| 700 | 1 | |a Sakuma |D Hajime |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | |
| 773 | 0 | |t International Journal of Clinical Oncology |d Springer Japan |g 20/3(2015-06-01), 499-507 |x 1341-9625 |q 20:3<499 |1 2015 |2 20 |o 10147 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10147-014-0741-z |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10147-014-0741-z |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ochiai |D Satoru |u Department of Radiation Oncology, Matsusaka Central Hospital, 102 Kobou Kawaimachi, 515-8566, Matsusaka, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yamakado |D Koichiro |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kodama |D Hiroshi |u Department of Radiology, Suzuka Central Hospital, 1275-53 Yamanohana Yasuduka-cho, 513-0818, Suzuka, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nomoto |D Yoshihito |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ii |D Noriko |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Takaki |D Haruyuki |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sakuma |D Hajime |u Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, 514-8507, Tsu, Mie, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t International Journal of Clinical Oncology |d Springer Japan |g 20/3(2015-06-01), 499-507 |x 1341-9625 |q 20:3<499 |1 2015 |2 20 |o 10147 | ||