Computer-aided liver volumetry: performance of a fully-automated, prototype post-processing solution for whole-organ and lobar segmentation based on MDCT imaging

Verfasser / Beitragende:
[Ghaneh Fananapazir, Mustafa Bashir, Daniele Marin, Daniel Boll]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/5(2015-06-01), 1203-1212
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0276-9  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0276-9 
245 0 0 |a Computer-aided liver volumetry: performance of a fully-automated, prototype post-processing solution for whole-organ and lobar segmentation based on MDCT imaging  |h [Elektronische Daten]  |c [Ghaneh Fananapazir, Mustafa Bashir, Daniele Marin, Daniel Boll] 
520 3 |a Purpose: To evaluate the performance of a prototype, fully-automated post-processing solution for whole-liver and lobar segmentation based on MDCT datasets. Materials and methods: A polymer liver phantom was used to assess accuracy of post-processing applications comparing phantom volumes determined via Archimedes' principle with MDCT segmented datasets. For the IRB-approved, HIPAA-compliant study, 25 patients were enrolled. Volumetry performance compared the manual approach with the automated prototype, assessing intraobserver variability, and interclass correlation for whole-organ and lobar segmentation using ANOVA comparison. Fidelity of segmentation was evaluated qualitatively. Results: Phantom volume was 1581.0±44.7mL, manually segmented datasets estimated 1628.0±47.8mL, representing a mean overestimation of 3.0%, automatically segmented datasets estimated 1601.9±0mL, representing a mean overestimation of 1.3%. Whole-liver and segmental volumetry demonstrated no significant intraobserver variability for neither manual nor automated measurements. For whole-liver volumetry, automated measurement repetitions resulted in identical values; reproducible whole-organ volumetry was also achieved with manual segmentation, p ANOVA 0.98. For lobar volumetry, automated segmentation improved reproducibility over manual approach, without significant measurement differences for either methodology, p ANOVA 0.95-0.99. Whole-organ and lobar segmentation results from manual and automated segmentation showed no significant differences, p ANOVA 0.96-1.00. Assessment of segmentation fidelity found that segments I-IV/VI showed greater segmentation inaccuracies compared to the remaining right hepatic lobe segments. Conclusion: Automated whole-liver segmentation showed non-inferiority of fully-automated whole-liver segmentation compared to manual approaches with improved reproducibility and post-processing duration; automated dual-seed lobar segmentation showed slight tendencies for underestimating the right hepatic lobe volume and greater variability in edge detection for the left hepatic lobe compared to manual segmentation. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a MDCT  |2 nationallicence 
690 7 |a Post-processing  |2 nationallicence 
690 7 |a Liver  |2 nationallicence 
690 7 |a Volumetry  |2 nationallicence 
700 1 |a Fananapazir  |D Ghaneh  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
700 1 |a Bashir  |D Mustafa  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
700 1 |a Marin  |D Daniele  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
700 1 |a Boll  |D Daniel  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/5(2015-06-01), 1203-1212  |x 0942-8925  |q 40:5<1203  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0276-9  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0276-9  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fananapazir  |D Ghaneh  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bashir  |D Mustafa  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Marin  |D Daniele  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Boll  |D Daniel  |u Department of Radiology, Duke University Medical Center, DUMC 3808, 27710, Durham, NC, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/5(2015-06-01), 1203-1212  |x 0942-8925  |q 40:5<1203  |1 2015  |2 40  |o 261