Isolation and characterization of a gamma-aminobutyric acid producing strain Lactobacillus buchneri WPZ001 that could efficiently utilize xylose and corncob hydrolysate

Verfasser / Beitragende:
[Anqi Zhao, Xiaoqing Hu, Lu Pan, Xiaoyuan Wang]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/7(2015-04-01), 3191-3200
Format:
Artikel (online)
ID: 605500398
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024 7 0 |a 10.1007/s00253-014-6294-2  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00253-014-6294-2 
245 0 0 |a Isolation and characterization of a gamma-aminobutyric acid producing strain Lactobacillus buchneri WPZ001 that could efficiently utilize xylose and corncob hydrolysate  |h [Elektronische Daten]  |c [Anqi Zhao, Xiaoqing Hu, Lu Pan, Xiaoyuan Wang] 
520 3 |a Lactobacillus buchneri strain WPZ001 that could efficiently produce gamma-aminobutyric acid was isolated from Chinese fermented sausages. Optimal cultivation conditions for gamma-aminobutyric acid production in L. buchneri WPZ001 were determined, and xylose was found to be the best carbon source. Using xylose as the sole carbon source, 70g/L gamma-aminobutyric acid was produced by flask fermentation of L. buchneri WPZ001 for 48h, and the harvested cells could continue to convert monosodium glutamate to gamma-aminobutyric acid in buffer and produce 59g gamma-aminobutyric acid after eight runs of biotransformation; the total yield of gamma-aminobutyric acid reached 129g/L. This combination strategy also worked well when the low-cost corncob hydrolysate was used as the sole carbon source, and the yield of gamma-aminobutyric acid reached 117g/L. The results indicate that L. buchneri WPZ001 has great potential for industrial production of gamma-aminobutyric acid. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a Lactobacillus buchneri  |2 nationallicence 
690 7 |a Gamma-aminobutyric acid  |2 nationallicence 
690 7 |a Xylose  |2 nationallicence 
690 7 |a Corncob hydrolysate  |2 nationallicence 
700 1 |a Zhao  |D Anqi  |u State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, China  |4 aut 
700 1 |a Hu  |D Xiaoqing  |u Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, China  |4 aut 
700 1 |a Pan  |D Lu  |u Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, China  |4 aut 
700 1 |a Wang  |D Xiaoyuan  |u State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, China  |4 aut 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/7(2015-04-01), 3191-3200  |x 0175-7598  |q 99:7<3191  |1 2015  |2 99  |o 253 
856 4 0 |u https://doi.org/10.1007/s00253-014-6294-2  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00253-014-6294-2  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zhao  |D Anqi  |u State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hu  |D Xiaoqing  |u Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pan  |D Lu  |u Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wang  |D Xiaoyuan  |u State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, China  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/7(2015-04-01), 3191-3200  |x 0175-7598  |q 99:7<3191  |1 2015  |2 99  |o 253