Estrogen Influences on Neuromuscular Function in Postmenopausal Women

Verfasser / Beitragende:
[S. Sipilä, T. Finni, V. Kovanen]
Ort, Verlag, Jahr:
2015
Enthalten in:
Calcified Tissue International, 96/3(2015-03-01), 222-233
Format:
Artikel (online)
ID: 605521263
LEADER caa a22 4500
001 605521263
003 CHVBK
005 20210128100739.0
007 cr unu---uuuuu
008 210128e20150301xx s 000 0 eng
024 7 0 |a 10.1007/s00223-014-9924-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00223-014-9924-x 
245 0 0 |a Estrogen Influences on Neuromuscular Function in Postmenopausal Women  |h [Elektronische Daten]  |c [S. Sipilä, T. Finni, V. Kovanen] 
520 3 |a Exposure to ovarian sex steroids during different life phases has long-term effects on women's health and wellbeing. Menopause is characterized by rapid decline in ovarian sex steroids already during mid-life, between the ages of 46 and 52. Due to the menopause-related hormonal changes, women in most western countries live more than one-third of their lives in postmenopausal status. The role of ovarian steroids on neuromuscular function in middle-aged and older women has been investigated since the 1980s with increasing volume of research during the last decades. This review considers how different components of the neuromuscular system may be influenced by estrogens and so affects neuromuscular function in postmenopausal women. The main focus is on muscle strength and power, which are closely associated with mobility and functional capacity among older populations. In the end of the review, we summarize recent findings on the underlying biological mechanisms in skeletal muscle that could explain the association between hormone replacement therapy and neuromuscular function among postmenopausal women. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Aging  |2 nationallicence 
690 7 |a Muscle strength  |2 nationallicence 
690 7 |a Hormone replacement therapy  |2 nationallicence 
690 7 |a IGF-1 pathway  |2 nationallicence 
690 7 |a MicroRNA  |2 nationallicence 
690 7 |a Myosin-actin cross-bridges  |2 nationallicence 
700 1 |a Sipilä  |D S.  |u Department of Health Sciences, Gerontology Research Center, University of Jyväskylä, Jyväskylä, Finland  |4 aut 
700 1 |a Finni  |D T.  |u Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, Jyväskylä, Finland  |4 aut 
700 1 |a Kovanen  |D V.  |u Department of Health Sciences, Gerontology Research Center, University of Jyväskylä, Jyväskylä, Finland  |4 aut 
773 0 |t Calcified Tissue International  |d Springer US; http://www.springer-ny.com  |g 96/3(2015-03-01), 222-233  |x 0171-967X  |q 96:3<222  |1 2015  |2 96  |o 223 
856 4 0 |u https://doi.org/10.1007/s00223-014-9924-x  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00223-014-9924-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sipilä  |D S.  |u Department of Health Sciences, Gerontology Research Center, University of Jyväskylä, Jyväskylä, Finland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Finni  |D T.  |u Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, Jyväskylä, Finland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kovanen  |D V.  |u Department of Health Sciences, Gerontology Research Center, University of Jyväskylä, Jyväskylä, Finland  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Calcified Tissue International  |d Springer US; http://www.springer-ny.com  |g 96/3(2015-03-01), 222-233  |x 0171-967X  |q 96:3<222  |1 2015  |2 96  |o 223