Implications of Exercise Training and Distribution of Protein Intake on Molecular Processes Regulating Skeletal Muscle Plasticity

Verfasser / Beitragende:
[Lee Margolis, Donato Rivas]
Ort, Verlag, Jahr:
2015
Enthalten in:
Calcified Tissue International, 96/3(2015-03-01), 211-221
Format:
Artikel (online)
ID: 60552128X
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024 7 0 |a 10.1007/s00223-014-9921-0  |2 doi 
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245 0 0 |a Implications of Exercise Training and Distribution of Protein Intake on Molecular Processes Regulating Skeletal Muscle Plasticity  |h [Elektronische Daten]  |c [Lee Margolis, Donato Rivas] 
520 3 |a To optimize its function, skeletal muscle exhibits exceptional plasticity and possesses the fundamental capacity to adapt its metabolic and contractile properties in response to various external stimuli (e.g., external loading, nutrient availability, and humoral factors). The adaptability of skeletal muscle, along with its relatively large mass and high metabolic rate, makes this tissue an important contributor to whole body health and mobility. This adaptational process includes changes in the number, size, and structural/functional properties of the myofibers. The adaptations of skeletal muscle to exercise are highly interrelated with dietary intake, particularly dietary protein, which has been shown to further potentiate exercise training-induced adaptations. Understanding the molecular adaptation of skeletal muscle to exercise and protein consumption is vital to elicit maximum benefit from exercise training to improve human performance and health. In this review, we will provide an overview of the molecular pathways regulating skeletal muscle adaptation to exercise and protein, and discuss the role of subsequent timing of nutrient intake following exercise. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Skeletal muscle  |2 nationallicence 
690 7 |a Exercise adaptation  |2 nationallicence 
690 7 |a Mitochondrial biogenesis  |2 nationallicence 
690 7 |a Muscle protein turnover  |2 nationallicence 
690 7 |a Dietary protein  |2 nationallicence 
690 7 |a Cellular signaling  |2 nationallicence 
700 1 |a Margolis  |D Lee  |u Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center On Aging, Tufts University, 711 Washington Street, 02111, Boston, MA, USA  |4 aut 
700 1 |a Rivas  |D Donato  |u Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center On Aging, Tufts University, 711 Washington Street, 02111, Boston, MA, USA  |4 aut 
773 0 |t Calcified Tissue International  |d Springer US; http://www.springer-ny.com  |g 96/3(2015-03-01), 211-221  |x 0171-967X  |q 96:3<211  |1 2015  |2 96  |o 223 
856 4 0 |u https://doi.org/10.1007/s00223-014-9921-0  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00223-014-9921-0  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Margolis  |D Lee  |u Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center On Aging, Tufts University, 711 Washington Street, 02111, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Rivas  |D Donato  |u Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center On Aging, Tufts University, 711 Washington Street, 02111, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Calcified Tissue International  |d Springer US; http://www.springer-ny.com  |g 96/3(2015-03-01), 211-221  |x 0171-967X  |q 96:3<211  |1 2015  |2 96  |o 223